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Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney

Title: Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney
Authors: Halimi JM; Sarafidis P; Azizi M; Bilo G; Burkard T; Bursztyn M; Camafort M; Chapman N; Cottone S; de Backer T; Deinum J; Delmotte P; Dorobantu M; Doumas M; Dusing R; Duly-Bouhanick B; Fauvel JP; Fesler P; Gaciong Z; Gkaliagkousi E; Gordin D; Grassi G; Grassos C; Guerrot D; Huart J; Izzo R; Jaén Águila F; Járai Z; Kahan T; Kantola I; Kociánová E; Limbourg F; Lopez-Sublet M; Mallamaci F; Manolis A; Marketou M; Mayer G; Mazza A; MacIntyre I; Mourad JJ; Muiesan ML; Nasr E; Nilsson P; Oliveras A; Ormezzano O; Paixão-Dias V; Papadakis I; Papadopoulos D; Perl S; Polónia J; Pontremoli R; Pucci G; Robles NR; Rubin S; Ruilope LM; Rump LC; Saeed S; Sanidas E; Sarzani R; Schmieder R; Silhol F; Sokolovic S; Solbu M; Soucek M; Stergiou G; Sudano I; Tabbalat R; Tengiz I; Triantafyllidi H; Tsioufis K; Václavík J; van der Giet M; der Niepen PV; Veglio F; Venzin R; Viigimaa M; Weber T; Widimsky J; Wuerzner G; Zelveian P; Zebekakis P; Lueders S; Persu A; Kreutz R; Vogt L.
Contributors: Halimi, J; Sarafidis, P; Azizi, M; Bilo, G; Burkard, T; Bursztyn, M; Camafort, M; Chapman, N; Cottone, S; de Backer, T; Deinum, J; Delmotte, P; Dorobantu, M; Doumas, M; Dusing, R; Duly-Bouhanick, B; Fauvel, J; Fesler, P; Gaciong, Z; Gkaliagkousi, E; Gordin, D; Grassi, G; Grassos, C; Guerrot, D; Huart, J; Izzo, R; Jaén Águila, F; Járai, Z; Kahan, T; Kantola, I; Kociánová, E; Limbourg, F; Lopez-Sublet, M; Mallamaci, F; Manolis, A; Marketou, M; Mayer, G; Mazza, A; Macintyre, I; Mourad, J; Muiesan, M; Nasr, E; Nilsson, P; Oliveras, A; Ormezzano, O; Paixão-Dias, V; Papadakis, I; Papadopoulos, D; Perl, S; Polónia, J; Pontremoli, R; Pucci, G; Robles, N; Rubin, S; Ruilope, L; Rump, L; Saeed, S; Sanidas, E; Sarzani, R; Schmieder, R; Silhol, F; Sokolovic, S; Solbu, M; Soucek, M; Stergiou, G; Sudano, I; Tabbalat, R; Tengiz, I; Triantafyllidi, H; Tsioufis, K; Václavík, J; van der Giet, M; der Niepen, P; Veglio, F; Venzin, R; Viigimaa, M; Weber, T; Widimsky, J; Wuerzner, G; Zelveian, P; Zebekakis, P; Lueders, S; Persu, A; Kreutz, R; Vogt, L
Publisher Information: Taylor & Francis; GB
Publication Year: 2024
Collection: Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive)
Subject Terms: Chronic kidney disease; guideline; hyperkalaemia; hypertension; management; mineralocorticoid receptor antagonist; RAS blocker; SGLT2 inhibitor
Description: Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representatives from 27 countries participated. According to the responders, renin-angiotensin system (RAS) blockers, calcium-channel blockers and thiazides were often added when these medications were lacking in CKD patients, but physicians were more prone to initiate RAS blockers (90% [interquartile range: 70–95%]) than MRA (20% [10–30%]), SGLT2i (30% [20–50%]) or (GLP1-RA (10% [5–15%]). Despite treatment optimisation, 30% of responders indicated that hypertension remained uncontrolled (30% (15–40%) vs 18% [10%–25%]) in CKD and CKD patients, respectively). Hyperkalemia was the most frequent barrier to initiate RAS blockers, and dosage reduction was considered in 45% of responders when kalaemia was 5.5–5.9 mmol/L. Conclusions RAS blockers are initiated in most ESH-ECS in CKD patients, but MRA and SGLT2i initiations are less frequent. Hyperkalemia was the main barrier for initiation or adequate dosing of RAS blockade, and RAS blockers’ dosage reduction was the usual management.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/38910347; info:eu-repo/semantics/altIdentifier/wos/WOS:001442781900001; volume:33; issue:1; journal:BLOOD PRESSURE; https://hdl.handle.net/10281/487600
DOI: 10.1080/08037051.2024.2368800
Availability: https://hdl.handle.net/10281/487600; https://doi.org/10.1080/08037051.2024.2368800
Rights: info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by-nc/4.0/
Accession Number: edsbas.7A61DF23
Database: BASE