| Title: |
Repeat it without me: Crowdsourcing the T1 mapping common ground via the ISMRM reproducibility challenge |
| Authors: |
Boudreau, Mathieu; Karakuzu, Agah; Cohen‐Adad, Julien; Bozkurt, Ecem; Carr, Madeline; Castellaro, Marco; Concha, Luis; Doneva, Mariya; Dual, Seraina A.; Ensworth, Alex; Foias, Alexandru; Fortier, Véronique; Gabr, Refaat E.; Gilbert, Guillaume; Glide‐Hurst, Carri K.; Grech‐Sollars, Matthew; Hu, Siyuan; Jalnefjord, Oscar; Jovicich, Jorge; Keskin, Kübra; Koken, Peter; Kolokotronis, Anastasia; Kukran, Simran; Lee, Nam G.; Levesque, Ives R.; Li, Bochao; Ma, Dan; Mädler, Burkhard; Maforo, Nyasha G.; Near, Jamie; Pasaye, Erick; Ramirez‐Manzanares, Alonso; Statton, Ben; Stehning, Christian; Tambalo, Stefano; Tian, Ye; Wang, Chenyang; Weiss, Kilian; Zakariaei, Niloufar; Zhang, Shuo; Zhao, Ziwei; Stikov, Nikola; null, null |
| Contributors: |
Boudreau, Mathieu; Karakuzu, Agah; Cohen‐adad, Julien; Bozkurt, Ecem; Carr, Madeline; Castellaro, Marco; Concha, Lui; Doneva, Mariya; Dual, Seraina A.; Ensworth, Alex; Foias, Alexandru; Fortier, Véronique; Gabr, Refaat E.; Gilbert, Guillaume; Glide‐hurst, Carri K.; Grech‐sollars, Matthew; Hu, Siyuan; Jalnefjord, Oscar; Jovicich, Jorge; Keskin, Kübra; Koken, Peter; Kolokotronis, Anastasia; Kukran, Simran; Lee, Nam G.; Levesque, Ives R.; Li, Bochao; Ma, Dan; Mädler, Burkhard; Maforo, Nyasha G.; Near, Jamie; Pasaye, Erick; Ramirez‐manzanares, Alonso; Statton, Ben; Stehning, Christian; Tambalo, Stefano; Tian, Ye; Wang, Chenyang; Weiss, Kilian; Zakariaei, Niloufar; Zhang, Shuo; Zhao, Ziwei; Stikov, Nikola; Null, Null |
| Publisher Information: |
WILEY |
| Publication Year: |
2024 |
| Collection: |
Padua Research Archive (IRIS - Università degli Studi di Padova) |
| Subject Terms: |
T1 mapping; inversion recovery; open data; quantitative MRI; reproducibility |
| Description: |
Purpose T-1 mapping is a widely used quantitative MRI technique, but its tissue-specific values remain inconsistent across protocols, sites, and vendors. The ISMRM Reproducible Research and Quantitative MR study groups jointly launched a challenge to assess the reproducibility of a well-established inversion-recovery T-1 mapping technique, using acquisition details from a seminal T-1 mapping paper on a standardized phantom and in human brains. Methods The challenge used the acquisition protocol from Barral et al. (2010). Researchers collected T-1 mapping data on the ISMRM/NIST phantom and/or in human brains. Data submission, pipeline development, and analysis were conducted using open-source platforms. Intersubmission and intrasubmission comparisons were performed. Results Eighteen submissions (39 phantom and 56 human datasets) on scanners by three MRI vendors were collected at 3 T (except one, at 0.35 T). The mean coefficient of variation was 6.1% for intersubmission phantom measurements, and 2.9% for intrasubmission measurements. For humans, the intersubmission/intrasubmission coefficient of variation was 5.9/3.2% in the genu and 16/6.9% in the cortex. An interactive dashboard for data visualization was also eveloped: https://rrsg2020.dashboards.neurolibre.org. Conclusion The T-1 intersubmission variability was twice as high as the intrasubmission variability in both phantoms and human brains, indicating that the acquisition details in the original paper were insufficient to reproduce a quantitative MRI protocol. This study reports the inherent uncertainty in T-1 measures across independent research groups, bringing us one step closer to a practical clinical baseline of T-1 variations in vivo. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/38730562; info:eu-repo/semantics/altIdentifier/wos/WOS:001218240800001; volume:92; issue:3; firstpage:1115; lastpage:1127; numberofpages:13; journal:MAGNETIC RESONANCE IN MEDICINE; https://hdl.handle.net/11577/3540398 |
| DOI: |
10.1002/mrm.30111 |
| Availability: |
https://hdl.handle.net/11577/3540398; https://doi.org/10.1002/mrm.30111 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.7B0103EE |
| Database: |
BASE |