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Definition of maximum daily amounts of vitamins and minerals allowed in food supplements: scientific rationale and European regulatory frameworks

Title: Definition of maximum daily amounts of vitamins and minerals allowed in food supplements: scientific rationale and European regulatory frameworks
Authors: Marangoni F; Fogacci F; Cicero AFG; Poli A.
Contributors: Marangoni, F; Fogacci, F; Cicero, Arrigo Francesco Giuseppe; Poli, A.
Publication Year: 2025
Collection: IRIS Università degli Studi di Bologna (CRIS - Current Research Information System)
Subject Terms: European nutrition and health claim regulation; dietary requirement; micronutrient; reference population; tolerable upper intake levels
Description: Ensuring an adequate supply of essential micronutrients while preventing excessive intakes that could lead to adverse effects presents a challenge in the context of food supplement regulation, in the absence of harmonization in the European Union. This paper examines the scientific rationale and regulatory frameworks governing the definition of maximum allowable levels for vitamins and minerals in food supplements. Existing legislation, scientific literature, and institutional documents were considered, focusing on the different factors influencing the risk-benefit assessment, such as dietary habits, selection of the reference population, and the contribution of fortified and enriched foods to total nutrient intake. While a precautionary approach has been proposed to prevent potential risks linked to excessive intakes, too restrictive limits may undermine the nutritional role of supplementation. Future regulatory frameworks should integrate both safety and efficacy considerations, ensuring that supplements contribute meaningfully to micronutrient adequacy while preventing excessively high intake levels.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/41403603; info:eu-repo/semantics/altIdentifier/wos/WOS:001621645400029; volume:21; issue:5; firstpage:2020; lastpage:2029; numberofpages:10; journal:ARCHIVES OF MEDICAL SCIENCES. ATHEROSCLEROTIC DISEASES; https://hdl.handle.net/11585/1039263
DOI: 10.5114/aoms/207235
Availability: https://hdl.handle.net/11585/1039263; https://doi.org/10.5114/aoms/207235; https://www.archivesofmedicalscience.com/Definition-of-maximum-daily-amounts-of-vitamins-and-minerals-allowed-in-food-supplements,207235,0,2.html
Rights: info:eu-repo/semantics/openAccess ; license:Licenza per Accesso Aperto. Creative Commons Attribuzione - Non commerciale - Condividi allo stesso modo (CCBYNCSA) ; license uri:iris.PUB19
Accession Number: edsbas.7B0E2BF2
Database: BASE