| Title: |
36 Assessing the Effect of Multiple Sclerosis and Aging Using an Ecological test of Prospective Memory |
| Authors: |
Charest, Kim; Potvin, Marie-Julie; Brando, Estefania; Tremblay, Alexandra; Roger, Elaine; Duquette, Pierre; Rouleau, Isabelle |
| Source: |
Journal of the International Neuropsychological Society ; volume 29, issue s1, page 550-551 ; ISSN 1355-6177 1469-7661 |
| Publisher Information: |
Cambridge University Press (CUP) |
| Publication Year: |
2023 |
| Description: |
Objective: Prospective memory (PM) is the ability to remember to produce an action at a specific moment in the future signaled by the occurrence of a specific event (EB condition), a time or a time interval (TB condition). Detection of the appropriate moment corresponds to the prospective component (PC), while production of the appropriate action corresponds to the retrospective (RC) component. Although PM difficulties have been reported in healthy aging and in association with Multiple Sclerosis (MS), PM has not been examined in elderly people with MS (PwMS), which is particularly relevant since their life expectancy has improved significantly in recent years due to available treatments, and PM is essential to daily functioning. The main objective of this study was to investigate whether the decline in PM performance with advancing age is influenced by the presence of multiple sclerosis (MS). This study also aimed to clarify the type of PM impairment (PC vs RC in TB and EB conditions) in MS as a function of age. Participants and Methods: A total of 80 participants were recruited and separated into four groups: elderly PwMS (n = 20), young PwMS (n = 20), elderly healthy controls (HC) (n = 20) and young HC (n = 20). PM and its components were measured using the TEMP, an experimental ecological tool developed by our laboratory that has been validated in previous studies. In addition, all participants underwent a series of neuropsychological tests specific to MS (MACIFMS) and aging (Boston Naming Test, Clock Drawing Test, Towers of London, Trail making Test, Stroop, MoCA). Results: On the TEMP total score, a two-way ANOVA showed a main effect of age (F[1,75]=47.4, p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1017/s1355617723007075 |
| Availability: |
https://doi.org/10.1017/s1355617723007075; https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S1355617723007075 |
| Rights: |
https://www.cambridge.org/core/terms |
| Accession Number: |
edsbas.7CD0FBA6 |
| Database: |
BASE |