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The role of esophagectomy in the management of Barrett's esophagus with high‐grade dysplasia

Title: The role of esophagectomy in the management of Barrett's esophagus with high‐grade dysplasia
Authors: Badgery, Henry; Read, Matthew; Winter, Nicole N.; Taylor, Andrew C. F.; Hii, Michael W.
Source: Annals of the New York Academy of Sciences ; volume 1481, issue 1, page 72-89 ; ISSN 0077-8923 1749-6632
Publisher Information: Wiley
Publication Year: 2020
Collection: Wiley Online Library (Open Access Articles via Crossref)
Description: Barrett's esophagus (BE) with high‐grade dysplasia (HGD) has previously been a routine indication for esophagectomy. Recent advances in endoscopic therapy have resulted in a shift away from surgery. Current international guidelines recommend endoscopic therapy for BE with HGD irrespective of recurrence or progression of dysplasia. Current guidelines do not address the ongoing role of esophagectomy as an adjunct in the setting of failed endoscopic therapy. This review examines the role of esophagectomy as an adjunct to endoscopy in the management of patients with BE and HGD, with a specific focus on patients with persistent, progressive, or recurrent disease, disease resistant to endoscopic therapy, in patients with concomitant esophageal pathology, and in those patients in whom lifelong surveillance may not be possible or desired.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1111/nyas.14439
Availability: https://doi.org/10.1111/nyas.14439; https://onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.14439; https://onlinelibrary.wiley.com/doi/full-xml/10.1111/nyas.14439; https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.14439
Rights: http://onlinelibrary.wiley.com/termsAndConditions#vor
Accession Number: edsbas.7CF924A0
Database: BASE