| Title: |
Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT) |
| Authors: |
Miro, Jose M; Malano-Barletta, Daniela; Berrocal, Leire; Manzardo, Christian; Castelli, Anna; Brunet, Mercè; Roman, Octavi; Ambrosioni, Juan; Cofán, Frederic; Gonzalez, Angela; Ruiz, Pablo; Crespo, Gonzalo; Forner, Alejandro; Ángeles Castel, M; Laguno, Montse; Tuset, Montse; de Lazzari, Elisa; Rimola, Antoni; Moreno, Asunción; Miro, J M; Malano, D; Manzardo, C; Castelli, A; Roman, O; Ambrosioni, J; Bodro, M; Linares, L; Laguno, M; Moreno, A; Rimola, A; Forner, A; Ruiz, P; Crespo, G; Londoño, M; Forns, X; Garcia-Valdecasas, J; Cofan, F; Diekmann, F; Oppenheimer, F; Castel, M A; Perez-Villa, F; Farrero, M; Pereda, D; Quintana, E; Brunet, M; Tuset, M; Paredes, D; López, H; Lligoña, A; Berrocal, L |
| Contributors: |
ViiV Healthcare |
| Source: |
Open Forum Infectious Diseases ; volume 12, issue 4 ; ISSN 2328-8957 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Background This study assessed the pharmacokinetic interactions between dolutegravir (DTG)-based antiretroviral therapy (ART) and immunosuppressants in solid organ transplantation (SOT) recipients with HIV and ART safety. Methods A phase IV, single-center, open-label, single-arm clinical trial (DTG-SOT, NCT03360682) including adult SOT recipients with HIV conducted between 2017 and 2019. People with HIV with plasma viral load |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ofid/ofaf119 |
| DOI: |
10.1093/ofid/ofaf119/62278799/ofaf119.pdf |
| Availability: |
https://doi.org/10.1093/ofid/ofaf119; https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofaf119/62278799/ofaf119.pdf; https://academic.oup.com/ofid/article-pdf/12/4/ofaf119/62278799/ofaf119.pdf |
| Rights: |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Accession Number: |
edsbas.7DC61B36 |
| Database: |
BASE |