| Title: |
A ‘click’ chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras |
| Authors: |
Cross, Jasmine M.; Coulson, Megan E.; Smalley, Joshua P.; Pytel, Wiktoria A.; Ismail, Ozair; Trory, Justin S.; Cowley, Shaun M.; Hodgkinson, James T. |
| Contributors: |
Engineering and Physical Sciences Research Council; Medical Research Council; Biotechnology and Biological Sciences Research Council |
| Source: |
RSC Medicinal Chemistry ; volume 13, issue 12, page 1634-1639 ; ISSN 2632-8682 |
| Publisher Information: |
Royal Society of Chemistry (RSC) |
| Publication Year: |
2022 |
| Description: |
Click chemistry was utilised to prepare a library of PROTACs based on entinostat a class I histone deacetylase (HDAC) inhibitor in clinical trials. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1039/d2md00199c |
| Availability: |
https://doi.org/10.1039/d2md00199c; http://pubs.rsc.org/en/content/articlepdf/2022/MD/D2MD00199C |
| Rights: |
http://creativecommons.org/licenses/by/3.0/ |
| Accession Number: |
edsbas.7DFD897F |
| Database: |
BASE |