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Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption

Title: Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption
Authors: Gondim, Marcos V. P.; Sherrill-Mix, Scott; Bibollet-Ruche, Frederic; Russell, Ronnie M.; Trimboli, Stephanie; Smith, Andrew G.; Li, Yingying; Liu, Weimin; Avitto, Alexa N.; DeVoto, Julia C.; Connell, Jesse; Fenton-May, Angharad E.; Pellegrino, Pierre; Williams, Ian; Papasavvas, Emmanouil; Lorenzi, Julio C. C.; Salantes, D. Brenda; Mampe, Felicity; Monroy, M. Alexandra; Cohen, Yehuda Z.; Heath, Sonya; Saag, Michael S.; Montaner, Luis J.; Collman, Ronald G.; Siliciano, Janet M.; Siliciano, Robert F.; Plenderleith, Lindsey J.; Sharp, Paul M.; Caskey, Marina; Nussenzweig, Michel C.; Shaw, George M.; Borrow, Persephone; Bar, Katharine J.; Hahn, Beatrice H.
Contributors: National Institutes of Health; Medical Research Council; Bill and Melinda Gates Foundation; NIH Office of the Director
Source: Science Translational Medicine ; volume 13, issue 576 ; ISSN 1946-6234 1946-6242
Publisher Information: American Association for the Advancement of Science (AAAS)
Publication Year: 2021
Description: Interferon-mediated pressures vary throughout HIV-1 infection but are the highest during viral rebound after treatment interruption.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1126/scitranslmed.abd8179
Availability: https://doi.org/10.1126/scitranslmed.abd8179; https://syndication.highwire.org/content/doi/10.1126/scitranslmed.abd8179; https://www.science.org/doi/pdf/10.1126/scitranslmed.abd8179
Accession Number: edsbas.7EAE20C8
Database: BASE