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MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review

Title: MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review
Authors: Dowling, L; Duseja, A; Vilaca, T; Walsh, JS; Goljanek-Whysall, K
Publisher Information: Wiley
Publication Year: 2022
Collection: The University of Liverpool Repository
Description: Sarcopenic obesity is a distinct condition of sarcopenia in the context of obesity, with the cumulative health risks of both phenotypes. Differential expression of microRNAs (miRNAs) has been reported separately in people with obesity and sarcopenia and may play a role in the pathogenesis of sarcopenic obesity. However, this has not been explored to date. This study aimed to identify differentially expressed miRNAs reported in serum, plasma, and skeletal muscle of people with obesity and sarcopenia and whether there are any commonalities between these conditions. We performed a systematic review on Embase and MEDLINE (PROSPERO, CRD42020224486) for differentially expressed miRNAs (fold change >1.5 or P-value
Document Type: article in journal/newspaper
Language: English
ISSN: 2190-5991
Relation: Dowling, L orcid:0000-0002-8332-358X , Duseja, A, Vilaca, T, Walsh, JS and Goljanek-Whysall, K orcid:0000-0001-8166-8800 (2022) MicroRNAs in obesity, sarcopenia, and commonalities for sarcopenic obesity: a systematic review Journal of Cachexia Sarcopenia and Muscle, 13 (1). pp. 68-85. ISSN 2190-5991, 2190-6009
DOI: 10.1002/jcsm.12878
Availability: https://livrepository.liverpool.ac.uk/3154327/; https://doi.org/10.1002/jcsm.12878
Accession Number: edsbas.7F723281
Database: BASE