| Title: |
Identification of Human Papillomavirus genotypes in juvenile laryngeal papillomatosis. Three-year experience in a concentration hospital in Puebla, Mexico: Identificación de genotipos de Virus del Papiloma Humano en papilomatosis laríngea juvenil. Experiencia de 3 años en un hospital de concentración en Puebla, México ; Identificación de genotipos de Virus del Papiloma Humano en papilomatosis laríngea juvenil. Experiencia de 3 años en un hospital de concentración en Puebla, México: Identification of Human Papillomavirus genotypes in juvenile laryngeal papillomatosis. Three-year experience in a concentration hospital in Puebla, Mexico |
| Authors: |
García-Galicia, Arturo; Andrade-Bonilla, Clotilde Margarita; Vallejo-Ruiz, Verónica; Vallejo-Domínguez, Blanca Elena; Ramírez-Mendoza, Janeth; Montiel-Jarquín, Álvaro José; Bertado-Ramírez, Nancy Rosalía; Loría-Castellanos, Jorge |
| Source: |
Revista de la Facultad de Medicina Humana; Vol. 23 Núm. 1 (2023): Revista de la Facultad de Medicina Humana ; Revista de la Facultad de Medicina Humana; Vol. 23 No. 1 (2023): Revista de la Facultad de Medicina Humana ; 2308-0531 ; 1814-5469 ; 10.25176/rfmh.v23i1 |
| Publisher Information: |
Universidad Ricardo Palma |
| Publication Year: |
2023 |
| Subject Terms: |
Español; Papiloma; Infecciones por Papillomavirus; Papillomavirus Humano 6; Papillomavirus Humano 11 |
| Description: |
Background: Juvenile laryngeal papillomatosis (JLP) is a chronic benign disease from viral etiology, whose clinical course can be aggressive. In Mexico, the Human Papillomavirus (HPV) genotypes that cause this disease have been poorly studied. Objective: To identify the HPV genotypes in patients with JLP in a reference Hospital in Puebla, Mexico. Mehods: A retrospective descriptive study was performed in patients with JLP attended in a 3rd level care of the Instituto Mexicano del Seguro Social in Puebla, México, from 2018 to 2021. Medical records were revised. In all patients, HPV identification was performed by polymerase chain reaction for genomes 6, 11, 16 and 18 using specific oligonucleotides. Descriptive statistics were applied. Results: 9 patients were included, 56% women, mean age 9.5 ±5.7 years; 7 patients were HPV-11 positive and 2 HPV-6. The mean age at diagnosis was 2.35 ±1.77 years, with an average of 12 ±11.56 surgical procedures; 5 patients were tracheostomy carriers, 4 had genotype 11; 8 patients were born vaginally, but no patient had maternal genital condylomatous lesions. In the patient born by cesarean section, transmission due to sexual abuse was documented. Conclusions: The most frequent genotypes in patients with JLP in the south-central region of Mexico are HPV-6 and HPV-11, the latter one is predominating. ; Introducción: La papilomatosis laríngea juvenil (PLJ) es una enfermedad benigna crónica de etiología viral, que tiende a tomar un curso clínico agresivo. En México se han estudiado pobremente los genotipos del Virus del Papiloma Humano (VPH) que causan la enfermedad. Objetivo: Identificar los genotipos del VPH en los pacientes con PLJ en un hospital de concentración en Puebla, México. Métodos: Se realizó un estudio descriptivo y retrospectivo a los pacientes con papilomatosis laríngea juvenil atendidos en un hospital de 3er nivel de atención del Instituto Mexicano del Seguro Social en Puebla, México, en el periodo 2018-2021. Se realizó revisión de expedientes clínicos. En todos los ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
text/html; application/pdf |
| Language: |
Spanish; Castilian; English |
| Relation: |
https://revistas.urp.edu.pe/index.php/RFMH/article/view/5088/7552; https://revistas.urp.edu.pe/index.php/RFMH/article/view/5088/7553; https://revistas.urp.edu.pe/index.php/RFMH/article/view/5088/7314; https://revistas.urp.edu.pe/index.php/RFMH/article/view/5088/7416; https://revistas.urp.edu.pe/index.php/RFMH/article/view/5088 |
| DOI: |
10.25176/rfmh.v23i1.5088 |
| Availability: |
https://revistas.urp.edu.pe/index.php/RFMH/article/view/5088; https://doi.org/10.25176/rfmh.v23i1.5088 |
| Rights: |
Derechos de autor 2023 Revista de la Facultad de Medicina Humana ; http://creativecommons.org/licenses/by/4.0 |
| Accession Number: |
edsbas.7F9CC50A |
| Database: |
BASE |