| Title: |
Long-term outcome of fat grafting to treat facial Systemic Sclerosis: a prospective cohort study |
| Authors: |
Almadori, Aurora; Griffin, Michelle; Hyun, Jeon; Hansen, Esther; Denton, Christopher P; Butler, Peter EM |
| Source: |
Plastic and Reconstructive Surgery , 156 (4) pp. 611-621. (2025) |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2025 |
| Collection: |
University College London: UCL Discovery |
| Description: |
Background: Systemic Sclerosis (SSc) is characterized by subcutaneous tissue loss and dermal fibrosis, with limited facial movement and mouth opening. Fat grafting is a minimally invasive technique used to restore facial volume and improve skin fibrosis. // Materials and methods: A cohort of 93 patients were assessed using 3D imaging (3dMD) before and after fat grafting. Secondary outcomes included physician-based assessment, mouth function (MHISS), psychological status, quality of life (DAS, HADS, VAS, BFNES), and patient-based satisfaction. // Results: After an average of 2.96 (±2.2) sessions of fat grafting, with an injection volume of 11.9 cc (±6) in each session, the overall retention rate was 53.1% (±0.17) at an average follow-up of 3.11 (±1.73) years. Patients undergoing 5+ interventions presented a higher retention rate (73.1% ±0.08%) than those receiving one or two treatments (45.2% ±0.09 and 50.5% ±0.15 respectively) (P |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10206885/1/long_term_outcome_of_fat_grafting_to_treat_facial.31.pdf; https://discovery.ucl.ac.uk/id/eprint/10206885/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10206885/1/long_term_outcome_of_fat_grafting_to_treat_facial.31.pdf; https://discovery.ucl.ac.uk/id/eprint/10206885/ |
| Rights: |
open |
| Accession Number: |
edsbas.80DE6643 |
| Database: |
BASE |