| Title: |
A Chemical Strategy for the Preparation of Multimodified Peptide Imaging Probes |
| Authors: |
De Rosa L.; Hawala I.; Di Stasi R.; Stefania R.; Capozza M.; Nava D.; D'Andrea L. D. |
| Contributors: |
De Rosa, L.; Hawala, I.; Di Stasi, R.; Stefania, R.; Capozza, M.; Nava, D.; D'Andrea, L. D. |
| Publication Year: |
2023 |
| Collection: |
Università degli Studi del Piemonte Orientale: CINECA IRIS |
| Description: |
Multimodality probes appear of great interest for innovative imaging applications in disease diagnosis. Herein, we present a chemical strategy enabling site-specific doublemodification and cyclization of a peptide probe exploiting native chemical ligation (NCL) and thiol-maleimide addition. The synthetic strategy is straightforward and of general applicability for the development of double-labeled peptide multimodality probes. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/36988421; info:eu-repo/semantics/altIdentifier/wos/WOS:000962162800001; volume:88; issue:7; firstpage:4546; lastpage:4553; numberofpages:8; journal:JOURNAL OF ORGANIC CHEMISTRY; https://hdl.handle.net/11579/153360 |
| DOI: |
10.1021/acs.joc.3c00014 |
| Availability: |
https://hdl.handle.net/11579/153360; https://doi.org/10.1021/acs.joc.3c00014 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.8134ACF |
| Database: |
BASE |