| Title: |
Impact of COVID-19 Pandemic on Management and Outcomes in Patients with Septic Shock in the Emergency Department |
| Authors: |
Jeong, Daun; Lee, Gun Tak; Park, Jong Eun; Shin, Tae Gun; Kim, Kyunga; Jang, Doeun; Kim, Won Young; Jo, You Hwan; Chung, Sung Phil; Beom, Jin Ho; Choi, Sung-Hyuk; Kwon, Woon Yong; Suh, Gil Joon; Ko, Byuk Sung; Han, Kap Su; Shin, Jong Hwan; Cho, Hanjin; Hwang, Sung Yeon |
| Contributors: |
Jo, You Hwan; Suh, Gil Joon; Shin, Jong Hwan |
| Publisher Information: |
MDPI AG |
| Publication Year: |
2022 |
| Collection: |
Seoul National University: S-Space |
| Subject Terms: |
GOAL-DIRECTED RESUSCITATION; DEFINITIONS; SOCIETY; VISITS; SEPSIS; COVID-19; septic shock; resuscitation; sepsis bundle; mortality |
| Description: |
This study aimed to determine the impact of modifications in emergency department (ED) practices caused by the coronavirus disease 2019 (COVID-19) pandemic on the clinical outcomes and management of patients with septic shock. We performed a retrospective study. Patients with septic shock who presented to the ED between 1 January 2018 and 19 January 2020 were allocated to the pre-COVID-19 group, whereas those who presented between 20 January 2020 and 31 December 2020 were assigned to the post-COVID-19 group. We used propensity score matching to compare the sepsis-related interventions and clinical outcomes. The primary outcome measure was in-hospital mortality. Of the 3697 patients included, 2254 were classified as pre-COVID-19 and 1143 as postCOVID-19. A total of 1140 propensity score-matched pairings were created. Overall, the in-hospital mortality rate was 25.5%, with no statistical difference between the pre- and post-COVID-19 groups (p = 0.92). In a matched cohort, the post-COVID-19 group had delayed lactate measurement, blood culture test, and infection source control (all p < 0.05). There was no significant difference in time to antibiotics (p = 0.19) or vasopressor administration (p = 0.09) between the groups. Although sepsis-related interventions were delayed during the COVID-19 pandemic, there was no significant difference in the in-hospital mortality between the pre- and post-COVID-19 groups. ; Y ; 1 |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| Relation: |
Journal of Personalized Medicine, Vol.12 No.11; https://hdl.handle.net/10371/188796; 000881289700001; 176455 |
| DOI: |
10.3390/jpm12111803 |
| Availability: |
https://hdl.handle.net/10371/188796; https://doi.org/10.3390/jpm12111803 |
| Accession Number: |
edsbas.81A3E322 |
| Database: |
BASE |