| Title: |
The baseline comorbidity burden affects survival in elderly patients with acute myeloid leukemia receiving hypomethylating agents: Results from a multicentric clinical study |
| Authors: |
Marconi G.; Candoni A.; Di Nicola R.; Sartor C.; Parisi S.; Abbenante M.; Nanni J.; Cristiano G.; Zannoni L.; Lazzarotto D.; Giannini B.; Baldazzi C.; Bandini L.; Ottaviani E.; Testoni N.; Bezzi C. D. G.; Abd-alatif R.; Ciotti G.; Fanin R.; Martinelli G.; Paolini S.; Ricci P.; Cavo M.; Papayannidis C.; Curti A. |
| Contributors: |
Marconi G.; Candoni A.; Di Nicola R.; Sartor C.; Parisi S.; Abbenante M.; Nanni J.; Cristiano G.; Zannoni L.; Lazzarotto D.; Giannini B.; Baldazzi C.; Bandini L.; Ottaviani E.; Testoni N.; Bezzi C.D.G.; Abd-alatif R.; Ciotti G.; Fanin R.; Martinelli G.; Paolini S.; Ricci P.; Cavo M.; Papayannidis C.; Curti A. |
| Publication Year: |
2023 |
| Collection: |
IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| Subject Terms: |
acute myeloid leukemia; elderly; fitne; hypomethylating agent; prognosis |
| Description: |
Background: In older patients with acute myeloid leukemia (AML), the definition of fitness, prognosis, and risk of death represents an open question. Methods: In the present study, we tested the impact on survival of disease- and patient-related parameters in a large cohort of elderly AML patients homogeneously assigned to treatment with hypomethylating agents (HMAs). Results: In 131 patients with a median age of 76 years, we confirmed that early response ( |
| Document Type: |
article in journal/newspaper |
| File Description: |
ELETTRONICO |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/36999931; info:eu-repo/semantics/altIdentifier/wos/WOS:000961396200001; volume:12; issue:10; firstpage:11838; lastpage:11848; numberofpages:11; journal:CANCER MEDICINE; https://hdl.handle.net/11585/954677 |
| DOI: |
10.1002/cam4.5858 |
| Availability: |
https://hdl.handle.net/11585/954677; https://doi.org/10.1002/cam4.5858; https://onlinelibrary.wiley.com/doi/10.1002/cam4.5858 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.8229A95 |
| Database: |
BASE |