| Title: |
Impact of relative change in temperature and atmospheric pressure on acute aortic syndrome occurrence in france |
| Authors: |
Guimbretiere, Guillaume; Nusinovici, Simon; Monnot, Antoine; Sobocinski, Jonathan; Senage, Thomas; Delsart, Pascal; Gourraud, Pierre-Antoine; Maurel, Blandine |
| Contributors: |
CHU Lille; Inserm; Université de Lille; ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 ITX-lab; Centre d’Investigation Clinique de Nantes CIC Nantes; Centre Hospitalier Régional Universitaire CHU Lille CHRU Lille; Advanced Drug Delivery Systems (ADDS) - U1008; Institut du Thorax Nantes; Centre d'investigation clinique (CIC) de Nantes -CIC Plurithématique CIC 0004 - Nantes |
| Publication Year: |
2024 |
| Collection: |
LillOA (Lille Open Archive - Université de Lille) |
| Description: |
Acute aortic syndromes (AAS) have been related to significant circadian and seasonal conditions. We used time series analyses to study the impact of meteorological variations on AAS occurrence. We retrospectively assessed 140 patients presenting with AAS over a 6-year period in a French university hospital. Average daily temperature (T) and atmospheric pressure (AP) at the location of the event were collected within the previous 10 days, and their association with AAS investigated with generalized additive models. A decrease in temperature of more than 5 °C within the previous seven days was significantly associated with an increased risk of AAS occurrence (OR equal to 1.86 [1.06; 3.44]). Subgroup analysis revealed that the risk was only significant among normotensive individuals (n = 41) free from blood pressure lowering medication (OR equal to 2.3 [1.05; 5.37]), but not among hypertensive individuals under blood pressure lowering medication despite a larger patient number (n = 99). Similarly, only among the subgroup of normotensive individuals a decrease of AP between 2 and 4 kPa within the previous 3 days was associated with an increased risk of AAS (OR equal to 2.93 [1.1; 8.15]) and an increased between 2 and 4 kPa was associated with a decreased risk (OR equal to 0.59 [0.36; 1.00]). Variations of meteorological conditions (temperature and AP) within the previous week seem to have effects on triggering AAS especially among the population free from blood pressure lowering medication. ; 10 |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/octet-stream; application/rdf+xml; charset=utf-8; application/pdf |
| Language: |
English |
| Relation: |
Scientific Reports; Sci Rep; http://hdl.handle.net/20.500.12210/36968 |
| Availability: |
https://hdl.handle.net/20.500.12210/36968 |
| Rights: |
Attribution 3.0 United States ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.827F62F7 |
| Database: |
BASE |