| Title: |
Abstracts: Cardio resynchronisation therapy - Outcomes |
| Authors: |
Ginks, M.; Hamid, S.; Bostock, J.; Mobb, M.; Razavi, R.; Rinaldi, C.A.; Foley, P.W.X.; Chalil, S.; Khadjooi, K.; Jordan, P.J.; Smith, R.E.A.; Frenneaux, M.P.; Leyva, F.; Leclercq, C.; Kranig, W.; Donal, E.; Calo, L.; Casella, M.; Delarche, N.; Boulogne, E.; Boriani, G.; the B-LEFT HF Investigators; Romanov, A.; Pokushalov, E.; Cherniavsky, A.; Prohorova, D.; Mc Grew, F.; Bank, A.; Yong, P.; Galle, E.; Boehmer, J.; COMPANION Investigators; Perez, D.; Berruezo, A.; Vatasescu, R.G.; Papiashvili, G.; Vidal, B.; Sitges, M.; Mont, L.; Brugada, J. |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2009 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Monday 22 June |
| Description: |
Introduction: We assessed the acute haemodynamic effect of dual site left ventricular (LV) pacing in patients undergoing CRT, as this may represent a strategy to improve response rates. Methods: 10 patients fulfilling criteria for CRT were studied. During the CRT procedure, a pressure wire was passed to the LV via the femoral or radial artery. After balloon occlusive venography, 2 guide sheaths were positioned in the coronary sinus and used to place 2 LV leads: one empirically in the posterolateral branch (LV1) and one in another vein (LV2, lateral in 6 cases and anterolateral in 4). Lead capture was confirmed and steady state pacing achieved. ≥3 Recordings of mean peak dP/dt max were taken over ≥10s each in intrinsic rhythm, with LV pacing in each vein & with dual site LV pacing at 100bpm. Results: 9 patients were male, 5 ischaemic and 5 non-ischaemic cardiomyopathy. 7 in sinus rhythm & 3 in atrial fibrillation. Age 65±11yrs, EF 26±7%, NYHA 2.6±0.5, QRS duration 165±32ms. All patients had successful placement of 2 coronary sinus leads. dP/dt max was 752±192mmHg/s in intrinsic rhythm. This improved by 206mmHg/s to 958±271mmHg/s with LV1 pacing (p=0.017) & by 84mmHg/s to 836±194mmHg/s with LV2 pacing (p=0.065). Dual site (LV1+LV2) pacing resulted in dP/dt max of 974±219mmHg/s (p=.001 compared with intrinsic). Dual site pacing conferred benefit over the less preferred (LV2) position (p |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://europace.oxfordjournals.org/cgi/content/short/11/suppl_2/NP-e; http://dx.doi.org/10.1093/europace/euq200 |
| DOI: |
10.1093/europace/euq200 |
| Availability: |
http://europace.oxfordjournals.org/cgi/content/short/11/suppl_2/NP-e; https://doi.org/10.1093/europace/euq200 |
| Rights: |
Copyright (C) 2009, European Heart Rhythm Association of the European Society of Cardiology (ESC) |
| Accession Number: |
edsbas.82EAE208 |
| Database: |
BASE |