| Title: |
Mother and child health 4.5 years after gestational diabetes mellitus managed using tight or less tight targets for glycaemic control: Post-hoc follow-up study of the TARGET trial |
| Authors: |
Douglas, Lisa J.; Gamble, Greg D.; Harding, Jane E.; Samuel, Deborah; Eagleton, Carl L.; Alsweiler, Jane M.; Wouldes, Trecia A.; Thompson, Benjamin; McKinlay, Christopher J. D.; Crowther, Caroline A. |
| Contributors: |
Myers, Jenny E; New Zealand Lottery Health Research Grant; Te Whatu Ora - Counties Manukau Tupu Fund; Auckland Medical Research Foundation |
| Source: |
PLOS Medicine ; volume 23, issue 2, page e1004635 ; ISSN 1549-1676 |
| Publisher Information: |
Public Library of Science (PLoS) |
| Publication Year: |
2026 |
| Collection: |
PLOS Publications (via CrossRef) |
| Description: |
Background Optimal glycaemic targets for women with gestational diabetes mellitus (GDM) are unclear. The aim of this study was to compare maternal and child health 4.5 years after women with GDM had been randomised to use tight or less tight targets for glycaemic control during their pregnancy. Methods and findings The TARGET trial was a stepped-wedge, cluster-randomised trial conducted between May 29, 2015 and November 7, 2017 at 10 hospitals in New Zealand. All hospitals were initially allocated to use less tight glycaemic treatment targets (fasting plasma glucose (FPG) |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1371/journal.pmed.1004635 |
| Availability: |
https://doi.org/10.1371/journal.pmed.1004635; https://dx.plos.org/10.1371/journal.pmed.1004635 |
| Rights: |
http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.8330064C |
| Database: |
BASE |