| Title: |
Malnutrition & inflammation in CKD 1-5 |
| Authors: |
Gursu, Meltem; Aydin, Zeki; Karadag, Serhat; Uzun, Sami; Ogul, Sabri; Kiris, Adem; Doventas, Yasemin; Koldas, Macit; Ozturk, Savas; Kazancioglu, Rumeyza; Mandreoli, Marcora; Bellasi, Antonio; Baldrati, Leopolodo; Corradini, Mattia; Rigotti, Angelo; Russo, Giorgia; David, Salvatore; Malmusi, Giulio; DiNicolo', Pierpaolo; Orsi, Claudio; Zambianchi, Loretta; Caruso, Francesco; Poisetti, Piegiorgio; Fabbri, Alba; Santoro, Antonio; Barton Pai, Amy; Grabe, Darren; Eisele, George; Hutchison, C.A.; Bevins, A.; Lukacik, P.; Hughes, R.G.; Pratt, G.; Viana, Joao L.; Bishop, Nicolette C.; Kosmadakis, George; Bevington, Alan; Clapp, Emma L.; Feehally, John; Smith, Alice C.; Joki, Nobuhiko; Hase, Hiroki; Tanaka, Yuri; Iwasaki, Masaki; Yamaka, Toshihiko; Shigematsu, Takashi; Dou, Laetitia; Gondouin, Bertrand; Cerini, Claire; Duval-Sabatier, Ariane; Poitevin, Stephane; Dignat-George, Françoise; Burtey, Stephane; Brunet, Philippe; Carrasco, Flávio; Salvador, Fábia; Origaça, Clarice; Nogueira, Eliana; Silva, Niels; Silva, Alvaro; Sikole, Aleksandar; Trajceska, Lada; Selim, Gjulsen; Gelev, Saso; Dzekova, Pavlina; Amitov, Vili; Arsov, Stefan; Dalboni, Maria; Cruz, Edgar; Manfredi, Silvia; Mouro, Margarete; Quinto, Marie; Grabulosa, Caren; Batista, Marcelo; Cendoroglo, Miguel; Hirayama, Aki; Matsui, Hirofumi; Nagano, Yumiko; Ueda, Atsushi; Aoyagi, Kazumasa; Owada, Shigeru; Schepers, Eva; Barreto, Daniela; Liabeuf, Sophie; Glorieux, Griet; Eloot, Sunny; Barreto, Felipe; Massy, Ziad; Vanholder, Raymond; Secara, Irina Florentina; Oleniuc, Mihaela; Nistor, Ionut; Onofriescu, Mihai; Covic, Adrian; Aguerrevere, Susana; Granada, Marisa; Bayés, Beatriu; Pastor, Maricruz; Sancho, Ana; Bonal, Jordi; Cañas, Laura; Lauzurica, Ricardo; Teixidó, Josep; Troya, Maribel; Romero, Ramón; Capitanini, Alessandro; D'Alessandro, Claudia; Ferretti, Valerio; Petrone, Isabella; Pasquariello, Giovanna; Cupisti, Adamasco; Parastayeva, Marina M.; Berseneva, Olga N.; Kucher, Anatoly G.; Ivanova, Galina T.; Smirnov, Aleksy V.; Kayukov, Ivan G.; Kayabasi, Hasan; Esmer, Serdar; Yilmaz, Zulfikar; Kadiroglu, Ali Kemal; Yilmaz, M. Emin; Radic, Josipa; Kovacic, Vedran; Radic, Mislav; Ljutic, Dragan; Sain, Milenka; Karakan, Sebnem; Sezer, Siren; Tutal, Emre; Ozdemir Acar, F. Nurhan; Bi, Guangyu; Xing, Changying; Chen, Rui; Romero-Garcia, Alma; Jacobo-Arias, Fabiola; Martin del Campo, Fabiola; González-Espinoza, Liliana; Pazarin, Leonardo; Cueto-Manzano, Alfonso M.; Panagoutsos, Stylianos; Kriki, Pelagia; Mourvati, Eythimia; Tziakas, Dimitrios; Chalikias, Georgios; Stakos, Dimitrios; Apostolakis, Stavros; Tsigalou, Christina; Gioka, Theodora; Konstantinides, Stavros; Vargemezis, Vasilios; Nascimento, Marcelo; Hayashi, Shirley; Seeberger, Astrid; Yamamoto, Tae; Qureshi, Abdul Rashid; Lind, Brita; Riella, Miguel; Brodin, Lars-Ake; Lindholm, Bengt; Meier, Pascal; Menne, Jan; Krüger, Karsten; Mooren, Frank Cristop; Weissmann, Norbert; Seimetz, Michael; Haller, Hermann; Gusev, Eugeny; Solomatina, Lilia; Zhuravleva, Julia; Striker, Gary; Uribarri, Jaime; Cai, Weijing; Goodman, Susan; Pyzik, Renata; Grosjean, Fabrizio; Vlassara, Helen; So, A.; Gimona, A.; Kiechle, T.; Shpilsky, A.; Schlesinger, N. |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2011 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Friday 24 June 2011 |
| Description: |
INTRODUCTION AND AIMS: It is well known that chronic inflammation manifesting itself with increased levels of cytokines is prevalent in uremic patients; and is related with increased cardiovascular morbidity and mortality. PTX-3 is produced in response to proinflammatory signals and stimulation of Toll-like receptors. It has been related with endothelial dysfunction, proteinuria and glomerular filtration rate. We aimed in our study to examine the relationship of PTX-3 with other well-known inflammatory markers and carotid intima media thickness (CIMT) in patients with stage four and five chronic kidney disease (CKD). METHODS: The study was a cross-sectional cohort with four groups: hemodialysis (HD), peritoneal dialysis (PD), pre-dialysis (stage-4 CKD) and control groups. Their PTX-3, IL-6, fibrinogen and hsCRP levels as well as CIMTs were recorded and correlated with each other. RESULTS: Levels of the inflammatory markers are presented in the table. Table:Levels of inflammatory markers. HD group (n=23)PD group (n=25)Pre-dialysis group (n=25)Control group (n=18)PTX-3 (ng/ml)3.58±4.292.15±2.751.29±2.360.73±0.96IL-6 (pg/ml)39.95±64.4346.6±101.224±49.2216.05±28.32hsCRP (mg/l)0,973±0,791,021±1,29 |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://ckj.oxfordjournals.org/cgi/content/short/4/suppl_2/4.s2.33; http://dx.doi.org/10.1093/ndtplus/4.s2.33 |
| DOI: |
10.1093/ndtplus/4.s2.33 |
| Availability: |
http://ckj.oxfordjournals.org/cgi/content/short/4/suppl_2/4.s2.33; https://doi.org/10.1093/ndtplus/4.s2.33 |
| Rights: |
Copyright (C) 2011, European Renal Association - European Dialysis and Transplant Assoc |
| Accession Number: |
edsbas.8350B90 |
| Database: |
BASE |