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Cardiac Sarcoidosis Is Uncommon in Patients with Isolated Sarcoid Uveitis: Outcome of 294 Cases

Title: Cardiac Sarcoidosis Is Uncommon in Patients with Isolated Sarcoid Uveitis: Outcome of 294 Cases
Authors: Mael Richard; Yvan Jamilloux; Pierre-Yves Courand; Laurent Perard; Cécile-Audrey Durel; Arnaud Hot; Carole Burillon; Isabelle Durieu; Mathieu Gerfaud-Valentin; Laurent Kodjikian; Pascal Seve
Source: Journal of Clinical Medicine, Vol 10, Iss 2146, p 2146 (2021)
Publisher Information: MDPI AG
Publication Year: 2021
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: sarcoidosis; uveitis; cardiac sarcoidosis; Medicine
Description: Recently, concerns have been raised about an increased risk of cardiac sarcoidosis in patients with sarcoid uveitis. While cardiac sarcoidosis has a high mortality burden, there is still a lack of precise data on this association. The objective of this study is to describe the frequency and type of cardiac complications associated with sarcoidosis of a large cohort of patients with sarcoid uveitis. We analyzed the cardiac outcomes of a monocentric retrospective cohort of consecutive adults with a diagnosis of sarcoid uveitis between January 2004 and March 2020 in a tertiary French university hospital. A total of 294 patients with a final diagnosis of sarcoid uveitis were included. At final follow-up, seven (2.4%) patients of the cohort had cardiac sarcoidosis. Cardiac sarcoidosis was more frequent among patients with previously reported systemic sarcoidosis ( p = 0.008). The prevalence of cardiac sarcoidosis among patients with sarcoid uveitis is low, but patients with previously diagnosed sarcoidosis or those who develop systemic sarcoidosis during follow-up appear to be at increased risk.
Document Type: article in journal/newspaper
Language: English
Relation: https://www.mdpi.com/2077-0383/10/10/2146; https://doaj.org/toc/2077-0383; https://doaj.org/article/b3467cf5ec0749fc96618b7f371ec7ad
DOI: 10.3390/jcm10102146
Availability: https://doi.org/10.3390/jcm10102146; https://doaj.org/article/b3467cf5ec0749fc96618b7f371ec7ad
Accession Number: edsbas.843E697D
Database: BASE