| Title: |
Tragopogon Porrifolius improves serum lipid profile and increases short‐term satiety in rats |
| Authors: |
Zeeni, Nadine; Daher, Costantine F; Mroueh, Mohammad |
| Source: |
The FASEB Journal ; volume 26, issue S1 ; ISSN 0892-6638 1530-6860 |
| Publisher Information: |
Wiley |
| Publication Year: |
2012 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Tragopogon Porrifolius is an edible plant commonly used in folk medicine in Mediterranean countries. This study investigates the potential role of aqueous extract of the aerial part of T. porrifolius in lipemia, and appetite regulation using the rat model. Food intake, abdominal fat percent, blood lipid profile, liver weights and liver enzymes were assessed after 4 weeks of extract intake via drinking water (50, 100, or 250 mg/kg bodyweight) in standard and high‐fat dietary conditions. In a separate study, the short term effect of T. porrifolius water extract on food intake was assessed. Results showed that treatment for four weeks with the plant extract caused a marked improvement in the lipid profile (triglycerides, total cholesterol, LDL cholesterol, and HDL cholesterol). Body weight, food intake and intra‐abdominal fat were also lower in animals given the plant extract at doses of 100 and 250 mg/kg body weight. In addition, T. porrifolius extract preload produced a dose dependent decrease in food intake observed over 24 hours. In conclusion, the aqueous extract of T. porrifolius exhibited potential benefits in lipemia and increased satiety with no visible adverse effect. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1096/fasebj.26.1_supplement.1025.15 |
| Availability: |
http://dx.doi.org/10.1096/fasebj.26.1_supplement.1025.15 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.84A13944 |
| Database: |
BASE |