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Usability and feasibility of INFORMA platform for computerized cognitive stimulation in mild cognitive impairment and early dementia: an 8-week multicenter study

Title: Usability and feasibility of INFORMA platform for computerized cognitive stimulation in mild cognitive impairment and early dementia: an 8-week multicenter study
Authors: Basso, Cristina; Zanella, Andrea; Simoni, Marco; Fantozzi, Carlo; Gollin, Donata; Ruaro, Cristina; Tiozzo Netti, Silvia; Zapparoli, Alessandra; Padoan, Roberta; Gallucci, Maurizio; Gallo, Livia; Valentinis, Luca; Ceci, Moira; Dal Santo, Pierluigi; Ceccon, Anna; Pradelli, Samantha; Marcon, Michela; De Togni, Laura; Musso, Anna Maria; Riolo, Antonino; Gagni, Giuseppe; Gabelli, Carlo; Spano, Pierangelo; null, null
Contributors: Basso, Cristina; Zanella, Andrea; Simoni, Marco; Fantozzi, Carlo; Gollin, Donata; Ruaro, Cristina; Tiozzo Netti, Silvia; Zapparoli, Alessandra; Padoan, Roberta; Gallucci, Maurizio; Gallo, Livia; Valentinis, Luca; Ceci, Moira; Dal Santo, Pierluigi; Ceccon, Anna; Pradelli, Samantha; Marcon, Michela; De Togni, Laura; Musso, Anna Maria; Riolo, Antonino; Gagni, Giuseppe; Gabelli, Carlo; Spano, Pierangelo; Null, Null
Publication Year: 2026
Collection: Padua Research Archive (IRIS - Università degli Studi di Padova)
Description: Background: Mild cognitive impairment (MCI) and dementia represent significant global health challenges requiring innovative intervention approaches. Computerized cognitive training (CCT) offers promising alternatives to traditional face-to-face interventions, providing flexibility and personalized care for individuals with cognitive disorders. Aims: This study evaluated the usability of INFORMA, a novel software platform based on Cognitive Activation Therapy (CAT), for delivering telerehabilitation to participants with MCI and mild-to-moderate dementia. Methods: A prospective, non-interventional multicenter study enrolled 241 participants (MMSE 20-30, CDR 0.5-1) from 12 Italian Centers for Cognitive Disorders and Dementia. Participants engaged in an 8-week tablet-based telerehabilitation program with weekly supervision. Usability was assessed using the System Usability Scale (SUS), Task Completion Rate (TCR), and Relative Task Completion Time (R-TCT), supplemented by participant and caregiver questionnaires. Results: Of 219 completing participants (mean age 73.5 years), the mean SUS score was 82.0 (95% CI: 80.3-83.8), with 84% exceeding the usability threshold (SUS score > 68). Mean TCR reached 97.8%, while 70.3% demonstrated improved R-TCT. Higher SUS scores correlated with education and MMSE scores but decreased with age. Satisfaction ratings exceeded 87% for participants and 95% for caregivers. Discussion: INFORMA demonstrated high usability across all educational and cognitive levels, with the hybrid model combining automated exercises and professional supervision being well-received. Conclusions: INFORMA showed significant promise as a user-friendly computerized cognitive stimulation tool, supporting its potential efficacy for MCI and dementia interventions and warranting further therapeutic efficacy studies.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/41824213; journal:AGING CLINICAL AND EXPERIMENTAL RESEARCH; https://hdl.handle.net/11577/3585998
DOI: 10.1007/s40520-026-03346-y
Availability: https://hdl.handle.net/11577/3585998; https://doi.org/10.1007/s40520-026-03346-y
Rights: info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by-nc-nd/4.0/
Accession Number: edsbas.84B89B0B
Database: BASE