| Title: |
No association between breast pain and breast cancer:a prospective cohort study of 10 830 symptomatic women presenting to a breast cancer diagnostic clinic |
| Authors: |
Dave, Rajiv V; Bromley, Hannah; Taxiarchi, Vicky P; Camacho, Elizabeth; Chatterjee, Sumohan; Barnes, Nicola; Hutchison, Gillian; Bishop, Paul; Hamilton, William; Kirwan, Cliona C; Gandhi, Ashu |
| Source: |
Dave, R V, Bromley, H, Taxiarchi, V P, Camacho, E, Chatterjee, S, Barnes, N, Hutchison, G, Bishop, P, Hamilton, W, Kirwan, C C & Gandhi, A 2022, 'No association between breast pain and breast cancer : a prospective cohort study of 10 830 symptomatic women presenting to a breast cancer diagnostic clinic', The British journal of general practice : the journal of the Royal College of General Practitioners, vol. 72, no. 717, pp. e234-e243. https://doi.org/10.3399/BJGP.2021.0475 |
| Publication Year: |
2022 |
| Collection: |
The University of Manchester: Research Explorer - Publications |
| Subject Terms: |
Breast Neoplasms/diagnosis; Cost-Benefit Analysis; Female; Humans; Mastodynia; Prospective Studies; Quality-Adjusted Life Years; State Medicine |
| Description: |
BACKGROUND: Women with breast pain constitute >20% of breast clinic attendees. AIM: To investigate breast cancer incidence in women presenting with breast pain and establish the health economics of referring women with breast pain to secondary care. DESIGN AND SETTING: A prospective cohort study of all consecutive women referred to a breast diagnostic clinic over 12 months. METHOD: Women were categorised by presentation into four distinct clinical groups and cancer incidence investigated. RESULTS: Of 10 830 women, 1972 (18%) were referred with breast pain, 6708 (62%) with lumps, 480 (4%) with nipple symptoms, 1670 (15%) with 'other' symptoms. Mammography, performed in 1112 women with breast pain, identified cancer in eight (0.7%). Of the 1972 women with breast pain, breast cancer incidence was 0.4% compared with ∼5% in each of the three other clinical groups. Using 'breast lump' as reference, the odds ratio (OR) of women referred with breast pain having breast cancer was 0.05 (95% confidence interval = 0.02 to 0.09, P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| ISSN: |
0960-1643; 1478-5242 |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/34990395; info:eu-repo/semantics/altIdentifier/pissn/0960-1643; info:eu-repo/semantics/altIdentifier/eissn/1478-5242 |
| DOI: |
10.3399/BJGP.2021.0475 |
| Availability: |
https://research.manchester.ac.uk/en/publications/25753536-f2c7-48d8-b263-d619749db0af; https://doi.org/10.3399/BJGP.2021.0475 |
| Rights: |
info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.84C2E8EB |
| Database: |
BASE |