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DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia

Title: DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia
Authors: Lam, L. K. Metthew; Murphy, Sophia; Kokkinaki, Dimitra; Venosa, Alessandro; Sherrill-Mix, Scott; Casu, Carla; Rivella, Stefano; Weiner, Aaron; Park, Jeongho; Shin, Sunny; Vaughan, Andrew E.; Hahn, Beatrice H.; Odom John, Audrey R.; Meyer, Nuala J.; Hunter, Christopher A.; Worthen, G. Scott; Mangalmurti, Nilam S.
Source: Science Translational Medicine ; volume 13, issue 616 ; ISSN 1946-6234 1946-6242
Publisher Information: American Association for the Advancement of Science (AAAS)
Publication Year: 2021
Description: Red blood cells detect and bind cell-free nucleic acids, contributing to anemia and immune cell activation during acute inflammation.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1126/scitranslmed.abj1008
Availability: https://doi.org/10.1126/scitranslmed.abj1008; https://www.science.org/doi/pdf/10.1126/scitranslmed.abj1008
Accession Number: edsbas.85121D45
Database: BASE