| Title: |
Maternal and perinatal outcomes of sickle cell disease in pregnancy: A nationwide study in France |
| Authors: |
Corsia, Alice; Joseph, Laure; Beeker, Nathanael; Manceau, Sandra; Driessen, Marine; Meunier, Benoit; Cavazzana, Marina; Collier, Mathis; Treluyer, Jean‐Marc |
| Source: |
British Journal of Haematology ; volume 206, issue 4, page 1218-1227 ; ISSN 0007-1048 1365-2141 |
| Publisher Information: |
Wiley |
| Publication Year: |
2025 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Summary This nationwide cohort study provides a comprehensive overview of maternal and perinatal outcomes associated with sickle cell disease (SCD) during pregnancy. Using the French national health database, all singleton pregnancy‐related hospital discharges from 2013 to 2020 in women aged 15–55 ( n = 5 752 080) were selected. Of these, 1022 births were to women with SCD, 308 of whom were on long‐term treatment, that is, hydroxyurea (HU) and/or transfusion programme. Pregnancies with SCD were more likely to involve pre‐eclampsia (9.6% vs. 1.7%; p < 0.001), pulmonary embolism (0.70% vs. 0.02%; p < 0.001), caesarean sections (52.8% vs. 18.2%; p < 0.001) and postpartum haemorrhage (8.3% vs. 4.1%; p < 0.001) compared to pregnancies without SCD. Preterm birth ( |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1111/bjh.20009 |
| Availability: |
https://doi.org/10.1111/bjh.20009; https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.20009 |
| Rights: |
http://creativecommons.org/licenses/by-nc/4.0/ |
| Accession Number: |
edsbas.853565D7 |
| Database: |
BASE |