| Title: |
Early treatment with inhibitors of P2Y12 receptor in patients with ST-segment elevation myocardial infarction — 2023 ESC recommendations and scientific evidence. Is clinical evidence sufficient to suggest a move towards precision medicine? The ELECTRA-SIRIO 2 investigators’ viewpoint / |
| Authors: |
Kubica, Jacek; Adamski, Piotr; Badarienė, Jolita; Bonaca, Marc; Buszman, Piotr; Gabulova, Rahima; Gajda, Robert; Geisler, Tobias; Gil, Robert; Gorog, Diana A.; Gurbel, Paul A.; Hajdukiewicz, Tomasz; Hudzik, Bartosz; James, Stefan; Jeong, Young-Hoon; Kern, Adam; Kochman, Wacław; Kubica, Aldona; Kuliczkowski, Wiktor; Magielski, Przemysław; Niezgoda, Piotr; Ostrowska, Małgorzata; Raggi, Paolo; Rahimov, Uzeyir; Skonieczny, Grzegorz; Siller-Matula, Jolanta M.; Specchia, Giuseppe; Szarpak, Łukasz; Szymański, Paweł; Tantry, Udaya; Umińska, Julia; Navarese, Eliano Pio |
| Source: |
Cardiology journal., Gdansk : Via Medica, 2025, vol. 32, no. 2, p. 189-194. ; ISSN 1897-5593 ; eISSN 1898-018X |
| Publication Year: |
2025 |
| Collection: |
Vilnius University Virtual Library (VU VL) / Vilniaus universitetas virtuali biblioteka |
| Subject Terms: |
ACS; ESC guidelines; P2Y12; pretreatment; STEMI |
| Description: |
The 2023 ESC guidelines changed the previously recommended strategy of early treatment in patients with STEMI. Pre-treatment with a P2Y12 receptor inhibitor may be considered in patients undergoing a primary PCI strategy (Class IIb, Level of evidence B). However, the available scientific evidence justifies a personalized approach differentiating the indications for pre-treatment with oral P2Y12 receptor inhibitors depending on the concomitant administration of opioids. In our opinion, in patients undergoing primary PCI not treated with opioids, pre-treatment with an oral P2Y12 receptor inhibitor should be applied, while in patients undergoing primary PCI treated with opioids, pre-treatment with an oral P2Y12 receptor inhibitor should be considered. (Cardiol J 2025; 32, 2: 189–194). |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://epublications.vu.lt/object/elaba:235025697/235025697.pdf; https://repository.vu.lt/VU:ELABAPDB235025697&prefLang=en_US |
| Availability: |
https://repository.vu.lt/VU:ELABAPDB235025697&prefLang=en_US |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.8592DBDC |
| Database: |
BASE |