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Blood lactate in mild and moderate ARDS secondary to SARS COV 2

Title: Blood lactate in mild and moderate ARDS secondary to SARS COV 2
Authors: Pagano, A; Porta, G; Bosso, G; Allegorico, E; Serra, C; Mercurio, V; Sansone, G; Orefice, S; Numis, F G
Contributors: Pagano, A; Porta, G; Bosso, G; Allegorico, E; Serra, C; Mercurio, V; Sansone, G; Orefice, S; Numis, F G
Publication Year: 2023
Collection: IRIS Università degli Studi di Napoli Federico II
Description: Background and objectives: Elevated blood lactate levels are associated with poor outcome in several critical conditions. Patients with SARS-CoV-2 rarely develop hyperlactatemia. The purpose of this study is to evaluate the trend of lactatemia in patients affected by mild/moderate SARS-Co V-2-ARDS and if it affected prognosis. Methods: We analyzed blood lactate levels in thirty-eight patients with severe SARS-CoV-2 infection admitted to COVID Care Unit of Santa Maria delle Grazie Hospital, Pozzuoli. Results: Twenty patients survived and were discharged at home and 18 patients died. Despite severe hypoxia that affected all patients enrolled, T0 lactate was within normal values. All survivors showed a significant increase in lactate concentration the day prior to clinical improvement. In not-survivors levels of lactate did not increase significantly. Conclusion: In our study, patients who survive SARS CoV-2 ARDS have a fleeting increase in lactate, which precedes clinical improvement by one day.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000964524900001; volume:66; firstpage:73; lastpage:75; numberofpages:3; journal:THE AMERICAN JOURNAL OF EMERGENCY MEDICINE; https://hdl.handle.net/11588/931683
DOI: 10.1016/j.ajem.2023.01.032
Availability: https://hdl.handle.net/11588/931683; https://doi.org/10.1016/j.ajem.2023.01.032
Rights: info:eu-repo/semantics/restrictedAccess ; license:Non specificato ; license uri:na
Accession Number: edsbas.85C685ED
Database: BASE