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Idiopathic neonatal aortic arch thrombosis: A case report

Title: Idiopathic neonatal aortic arch thrombosis: A case report
Authors: Lofù, Ignazio; DI MAURO, ANTONIO; Di Coste, Antonio; Scalini, Egisto; Basile, Vincenzo; Codazzi, Daniela; LAFORGIA, Nicola; MANZIONNA, MARIANO
Contributors: Lofù, Ignazio; DI MAURO, Antonio; Di Coste, Antonio; Scalini, Egisto; Basile, Vincenzo; Codazzi, Daniela; Laforgia, Nicola; Manzionna, Mariano
Publication Year: 2014
Collection: Università degli Studi di Bari Aldo Moro: CINECA IRIS
Subject Terms: Medicine (all)
Description: Background: Neonatal aortic arch thrombosis is a rare but life threatening condition. A correct diagnosis and an appropriate therapeutic approach are fundamental to prevent death or severe injuries. Case presentation: we report a case of spontaneous aortic arch thrombosis in a term newborn, who presented with suggestive signs of aortic coarctation immediately after birth. Despite the initiation of anticoagulant therapy, a massive increase in size of thrombus with evidence of coronary involvement was noted. Thrombolytic treatment was performed with thrombus resolution. Death occurred after a few days due to widespread brain haemorrhage. Conclusion: To date, no definitive guidelines have been published for the treatment of neonatal aortic arch thrombosis, and only anecdotal reports are available. A multidisciplinary approach is fundamental in order to evaluate the risk:benefit ratio of proposed medical and surgical interventions. Further studies are needed to improve consensus evidence based guidelines and ensure appropriate approaches to this condition. © Euromediterranean Biomedical Journal 2014.
Document Type: article in journal/newspaper
Language: English
Relation: volume:9; firstpage:36; lastpage:40; numberofpages:5; journal:EUROMEDITERRANEAN BIOMEDICAL JOURNAL; https://hdl.handle.net/11586/177606; http://www.embj.org/images/ISSUE_2014/manzionna_5.pdf
DOI: 10.3269/1970-5492.2014.9.5
Availability: https://hdl.handle.net/11586/177606; https://doi.org/10.3269/1970-5492.2014.9.5; http://www.embj.org/images/ISSUE_2014/manzionna_5.pdf
Accession Number: edsbas.87677BC9
Database: BASE