| Title: |
Comparison of high ribavirin induction versus standard ribavirin dosing, plus peginterferon-α for the treatment of chronic hepatitis C in HIV-infected patients: the PERICO trial |
| Authors: |
Labarga, Pablo; Barreiro, Pablo; Silva, Alfredo da; Guardiola, Josep María; Rubio, Rafael; Aguirrebengoa, Koldo; Miralles, Pilar; Portu, Joseba; Téllez, María Jesús; Morano, Luis; Castro-Iglesias, Ángeles; Pineda, Juan A.; Terrón, Alberto; Hernández-Quero, José; Mariño, Ana; Ríos, María José; Echeverría, Santiago; Asensi, Víctor; Vispo, Eugenia; Soriano, Vicente |
| Publisher Information: |
Oxford |
| Publication Year: |
2012 |
| Collection: |
RUC - Repositorio Universidade Coruña |
| Subject Terms: |
Antiretroviral therapy highly active; Antiviral agents; Dose-Response relationship; Drug therapy-Combination; HIV infection; Hepacivirus; Hepatitis C; Interferon-alpha; Polyethylene glycols; RNA viral; Recombinant proteins; Ribavirin |
| Description: |
[Abstract] BACKGROUND: Ribavirin (RBV) exposure seems to be critical to maximize treatment response in human immunodeficiency virus (HIV)-positive patients with chronic hepatitis C virus (HCV) infection. METHODS: HIV/HCV-coinfected individuals naive to interferon were prospectively randomized to receive peginterferon-α-2a (180 μg/d) plus either RBV standard dosing (1000 or 1200 mg/d if |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://doi.org/10.1093/infdis/jis449; https://hdl.handle.net/2183/21607 |
| Availability: |
https://hdl.handle.net/2183/21607 |
| Rights: |
This is a pre-copyedited, author-produced version of an article accepted for publication in The Journal of Infectiuos Diseases following peer review. The version of record is avaliable online at Oxford Academic web. ; open access |
| Accession Number: |
edsbas.87C8663 |
| Database: |
BASE |