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Rhythm or rate control strategy in CRT recipients with long-standing persistent atrial fibrillation - preliminary results of the PilotCRAfT study

Title: Rhythm or rate control strategy in CRT recipients with long-standing persistent atrial fibrillation - preliminary results of the PilotCRAfT study
Authors: Ciszewski, JB; Tajstra, M; Gadula-Gacek, E; Kowalik, I; Maciag, A; Chwyczko, T; Jankowska, A; Smolis-Bak, E; Firek, B; Zajac, D; Szwed, H; Pytkowski, M; Gasior, M; Sterlinski, M
Source: EP Europace ; volume 23, issue Supplement_3 ; ISSN 1099-5129 1532-2092
Publisher Information: Oxford University Press (OUP)
Publication Year: 2021
Description: Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): National Institute of Cardiology in Warsaw Statutory Grant Background The presence of atrial fibrillation (AF) in cardiac resynchronization therapy (CRT) recipients is common and AF is a marker of poorer CRT response. The negative influence of AF on CRT efficacy is mediated mainly by the drop of the effectively captured biventricular paced beats percentage (BiVp%) which should exceed 95-98% to warrant good CRT response. Sinus rhythm (SR) restoration may improve CRT efficacy which in turn may protect AF recurrence. However, there is lack of randomized studies comparing rhythm and rate control strategies in these patients. Purpose The purpose of the Pilot-CRAfT study (NCT01850277) was to compare the efficacy of rhythm vs rate control strategy in CRT patients with long-standing persistent or permanent atrial fibrillation. Methods The study included patients with CRT and permanent or persistent AF lasting for ≥6 months, resulting in BiVp%
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/europace/euab116.466
Availability: https://doi.org/10.1093/europace/euab116.466; http://academic.oup.com/europace/article-pdf/23/Supplement_3/euab116.466/38131909/euab116.466.pdf
Rights: https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model
Accession Number: edsbas.884D6781
Database: BASE