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Electrocardiographic localization of ventricular arrhythmias successfully ablated from the distal great cardiac vein

Title: Electrocardiographic localization of ventricular arrhythmias successfully ablated from the distal great cardiac vein
Authors: Chang, David; Gabriels, James; Vaishnav, Aditi; Kim, Beom S.; Coleman, Kristie; Khan, Mohammad; Maisel, Kyle; Ismail, Haisam; Goldner, Bruce; Willner, Jonathan; Mitra, Raman; John, Roy M.; Patel, Apoor; Epstein, Laurence M.; Mountantonakis, Stavros; Beldner, Stuart
Source: Journal of Cardiovascular Electrophysiology ; volume 31, issue 10, page 2668-2676 ; ISSN 1045-3873 1540-8167
Publisher Information: Wiley
Publication Year: 2020
Collection: Wiley Online Library (Open Access Articles via Crossref)
Description: Background Idiopathic ventricular arrhythmias (IVAs) from the left ventricular (LV) summit may be successfully ablated from the distal great cardiac vein (dGCV). Using a 12‐lead electrocardiogram (ECG) to localize IVAs that can be ablated from the dGCV is valuable for ablation planning. Objective To determine if a “w” wave, a notch in the Q wave in lead I, and other ECG features can identify IVAs that can be successfully ablated from the dGCV. Methods We reviewed outflow tract premature ventricular contraction (PVC) ablations performed at two centers between September 2010 and June 2018. Successful PVC ablations, in which the PVCs were mapped from the right ventricular outflow tract, coronary cusps, commissures, endocardial LV, and the coronary venous system including the dGCV were included. ECG characteristics were compared between patients with successful ablations in the dGCV and non‐dGCV sites. Results Of the 120 patients (age 56.8 ± 13.8 years, 45% female) that met the inclusion criteria, the dGCV was the successful ablation site in 18 patients (15%). Multivariate analysis with binary logistic regression showed that a “w” in lead I in combination with an early precordial pattern break and a maximum deflection index (MDI) ≥ 0.5 had sensitivity and specificity for a successful ablation in the dGCV of 94.4% and 96.1%, respectively. Conclusion Combining a “w” wave in lead I with an early precordial pattern break and an MDI ≥ 0.5 is highly sensitive and specific for identifying the dGCV as a successful ablation site for PVCs.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1111/jce.14650
Availability: https://doi.org/10.1111/jce.14650; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjce.14650; https://onlinelibrary.wiley.com/doi/pdf/10.1111/jce.14650; https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jce.14650
Rights: http://onlinelibrary.wiley.com/termsAndConditions#vor
Accession Number: edsbas.889160F0
Database: BASE