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The choice of test for detecting raised disease risk near a point source

Title: The choice of test for detecting raised disease risk near a point source
Authors: Bithell, J. F.
Source: Statistics in Medicine ; volume 14, issue 21-22, page 2309-2322 ; ISSN 0277-6715 1097-0258
Publisher Information: Wiley
Publication Year: 1995
Collection: Wiley Online Library (Open Access Articles via Crossref)
Description: This paper considers the problem of testing for excess risk near a point source of risk S , as might be postulated to exist near a nuclear installation, for example. The data are assumed to be in the form of counts in small areas for which expected numbers of cases have also been calculated by reference to national rates. It is shown how to derive the most powerful test against any given alternative hypothesis; such ‘linear risk score’ tests are further considered, particularly that which scores each case according to the reciprocal of the rank of the distance from S . These tests are compared with two tests due to Stone for general ordered alternatives and the important distinction is drawn between conditional and unconditional versions of the tests. Their behaviour is illustrated by application to data on childhood leukaemia in relation to nuclear installations in Britain.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1002/sim.4780142104
Availability: https://doi.org/10.1002/sim.4780142104; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fsim.4780142104; https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.4780142104
Rights: http://onlinelibrary.wiley.com/termsAndConditions#vor
Accession Number: edsbas.89A2F05F
Database: BASE