| Title: |
Impact of High Altitude on Dyspnea at Rest |
| Authors: |
Bianquis, C.; Fiamma, M.-N.; Day, T.; Wilson, R.; Zubieta, G.; Morelot-panzini, C.; Similowski, T.; Patout, M. |
| Source: |
American Journal of Respiratory and Critical Care Medicine ; volume 211, issue Supplement_1, page A2639-A2639 ; ISSN 1073-449X 1535-4970 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
RATIONALE: In lowlanders who ascend rapidly to high altitude, dyspnea is a symptom often found in cases of acute mountain sickness (AMS) and is constant in cases of acute pulmonary oedema (HAPE). However, the existence of dyspnea in healthy persons without other sign of AMS or HAPE at high altitude has not been studied. The aim of this study was to assess the prevalence, characteristics and physiological changes associated with dyspnea in healthy lowlanders after a rapid ascent to high altitude. METHODS: Twenty-six healthy participants (half female and male, aged 26 [24-35]: normal STAI-anxiety score) completed the multimensional dyspnea profile (MDP) at baseline (Calgary, Alberta, Canada, 1,048 meters above sea level) and after an ascent to 3650 meters (La Paz, Bolivia). Concurrent measures of breathing pattern variables and room air arterial blood gases were performed. RESULTS After 24 hours at high altitude, all participants reported dyspnea during room air resting breathing, with a MDP-A1 score (breathing discomfort) of 2 [2-4] in La Paz (LP) vs 0 [0-0] in Calgary (Cal) (p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1164/ajrccm.2025.211.abstracts.a2639 |
| Availability: |
https://doi.org/10.1164/ajrccm.2025.211.abstracts.a2639; https://academic.oup.com/ajrccm/article-pdf/211/Supplement_1/A2639/67030889/ajrccm_211_abstracts_a2639.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.8A294AD5 |
| Database: |
BASE |