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Inferior vena cava filter thromboprophylaxis in surgical cancer patients

Title: Inferior vena cava filter thromboprophylaxis in surgical cancer patients
Authors: Makary, Mina S.; Koso, Mensur; Yoder, Matthew
Source: Journal of Surgical Oncology ; volume 130, issue 2, page 257-264 ; ISSN 0022-4790 1096-9098
Publisher Information: Wiley
Publication Year: 2024
Collection: Wiley Online Library (Open Access Articles via Crossref)
Description: Background and Objectives This study evaluated the utilization and outcomes of inferior vena cava (IVC) filters as thromboprophylaxis in cancer patients undergoing surgery. Methods This single‐center retrospective study analyzed baseline patient characteristics and clinical outcomes of surgical cancer patients who received perioperative prophylactic IVC filters. Primary clinical endpoints included venous thromboembolism (VTE) incidence and filter complications. A statistical correlative analysis was conducted to identify risk factors related to pulmonary embolism (PE), deep vein thrombosis (DVT), and filter thrombi, as well as advanced technique filter removal and mortality at 6 months. Results A total of 252 surgical oncology patients (median age, 59; female 51%) received IVC filters for the perioperative prevention of PE. Primary surgical sites included spine ( n = 91, 36%), orthopedic extremity/joint ( n = 49, 19%), genitourinary ( n = 47, 19%), brain/cranial ( n = 40, 16%), abdominal ( n = 18, 7%), multisite ( n = 4, 2%), and chest ( n = 3, 1%). Moreover, 15% of patients experienced DVTs in the postplacement preretrieval period, while 2% ( n = 6) of patients experienced definitive PEs. A total of 36% of IVC filters were ultimately retrieved, with an average filter dwell time of 7.4 months. Complications occurred in one retrieval. Conclusion Prophylactic perioperative IVC filters in surgical cancer patients resulted in minimal complications while ultimately resulting in a low incidence of PE.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1002/jso.27734
Availability: https://doi.org/10.1002/jso.27734; https://onlinelibrary.wiley.com/doi/pdf/10.1002/jso.27734
Rights: http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.8A6B21E8
Database: BASE