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A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study

Title: A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study
Authors: Frank, Derk; Durand, Eric; Lauck, Sandra; Muir, Douglas F; Spence, Mark; Vasa-Nicotera, Mariuca; Wood, David; Saia, Francesco; Urbano-Carrillo, Cristóbal A; Bouchayer, Damien; Iliescu, Vlad Anton; Saint Etienne, Christophe; Leclercq, Florence; Auffret, Vincent; Asmarats, Lluis; Di Mario, Carlo; Veugeois, Aurelie; Maly, Jiri; Schober, Andreas; Nombela-Franco, Luis; Werner, Nikos; Gómez-Hospital, Joan Antoni; Mascherbauer, Julia; Musumeci, Giuseppe; Meneveau, Nicolas; Meurice, Thibaud; Mahfoud, Felix; De Marco, Federico; Seidler, Tim; Leuschner, Florian; Joly, Patrick; Collet, Jean-Philippe; Vogt, Ferdinand; Di Lorenzo, Emilio; Kuhn, Elmar; Disdier, Vicente Peral; Hachaturyan, Violetta; Lüske, Claudia M; Rakova, Radka; Wesselink, Wilbert; Kurucova, Jana; Bramlage, Peter; McCalmont, Gemma; null, null; Zielinski, Marie; Greinert, Daniel; Deutsch, Cornelia; Muir, Douglas; Thoenes, Martin; García, Carlos Lara; Chamorro, Beatriz; Claudel, Jean-Philippe; Perrier, Hervé; Frebault, Viktoria; Parasca, Catalina Andreea; Etienne, Christophe Saint; Lassouani, Katia; Zitouni, Wassim; Soltani, Sonia; Gal, Rosalie Le; Xarrie, Elena Jimenez; Ciardetti, Niccolo; Meucci, Francesco; Bagdadi, Imane; Kolinova, Lenka; Delle-Karth, Georg; Schuster, Claudia; Leitgeb, Marie-Christine; García, Esther Bernardo; Pozzi, María Aránzazu Ortega; Leick, Jürgen; Lauterbach, Michael; Waschbüsch, Hannah; Antoni, Joan; Muntané, Guillem; Daxböck, Julia Mascherbauer Olga; Butkovic, Mirela; Popescu, Simona; Perrero, Martina; Watbled, Stephanie; Delomez, Maxence; Scheller, Bruno; Ewen, Sebastian; Berger, Ann-Kathrin; Koch, Christina; Engel, Alexandra; Olivares, Paolo; Wolf, Frieder; Müller, Carolin; Hünermund, Maren; Konstandin, Mathias; Linz, Lisa; Ulbricht, Hannah; Siame, Sabrina; Amrane, Nassima Ait; Rosenzweig, Dow; Cefalo, Barbara; Wolf, Vera; Daunert, Jaume Maristany; de la Bandera Sanchez, Maria Carmen
Contributors: Frank, Derk; Durand, Eric; Lauck, Sandra; Muir, Douglas F; Spence, Mark; Vasa-Nicotera, Mariuca; Wood, David; Saia, Francesco; Urbano-Carrillo, Cristóbal A; Bouchayer, Damien; Iliescu, Vlad Anton; Saint Etienne, Christophe; Leclercq, Florence; Auffret, Vincent; Asmarats, Llui; Di Mario, Carlo; Veugeois, Aurelie; Maly, Jiri; Schober, Andrea; Nombela-Franco, Lui; Werner, Niko; Gómez-Hospital, Joan Antoni; Mascherbauer, Julia; Musumeci, Giuseppe; Meneveau, Nicola; Meurice, Thibaud; Mahfoud, Felix; De Marco, Federico; Seidler, Tim; Leuschner, Florian; Joly, Patrick; Collet, Jean-Philippe; Vogt, Ferdinand; Di Lorenzo, Emilio; Kuhn, Elmar; Disdier, Vicente Peral; Hachaturyan, Violetta; Lüske, Claudia M; Rakova, Radka; Wesselink, Wilbert; Kurucova, Jana; Bramlage, Peter; McCalmont, Gemma; null, null; Zielinski, Marie; Greinert, Daniel; Deutsch, Cornelia; Muir, Dougla; Thoenes, Martin; García, Carlos Lara; Chamorro, Beatriz; Claudel, Jean-Philippe; Perrier, Hervé; Frebault, Viktoria; Parasca, Catalina Andreea; Etienne, Christophe Saint; Lassouani, Katia; Zitouni, Wassim; Soltani, Sonia; Gal, Rosalie Le; Xarrie, Elena Jimenez; Ciardetti, Niccolo; Meucci, Francesco; Bagdadi, Imane; Kolinova, Lenka; Delle-Karth, Georg; Schuster, Claudia; Leitgeb, Marie-Christine; García, Esther Bernardo; Pozzi, María Aránzazu Ortega; Leick, Jürgen; Lauterbach, Michael; Waschbüsch, Hannah; Antoni, Joan
Publication Year: 2024
Collection: IRIS Università degli Studi di Bologna (CRIS - Current Research Information System)
Subject Terms: Aortic stenosi; Quality of care; Prospective registry; Transcatheter aortic valve implantation; TAVI; Clinical care; Health services
Description: Background and Aims There is significant potential to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of this study was to evaluate the effect of implementing BENCHMARK best practices on the efficiency and safety of TAVI in 28 sites in 7 European countries. Methods This was a study of patients with severe symptomatic aortic stenosis (AS) undergoing TAVI with balloon-expandable valves before and after implementation of BENCHMARK best practices. Principal objectives were to reduce hospital length of stay (LoS) and duration of intensive care stay. Secondary objective was to document patient safety. Results Between January 2020 and March 2023, 897 patients were documented prior to and 1491 patients after the implementation of BENCHMARK practices. Patient characteristics were consistent with a known older TAVI population and only minor differences. Mean LoS was reduced from 7.7 +/- 7.0 to 5.8 +/- 5.6 days (median 6 vs. 4 days; P < .001). Duration of intensive care was reduced from 1.8 to 1.3 days (median 1.1 vs. 0.9 days; P < .001). Adoption of peri-procedure best practices led to increased use of local anaesthesia (96.1% vs. 84.3%; P < .001) and decreased procedure (median 47 vs. 60 min; P < .001) and intervention times (85 vs. 95 min; P < .001). Thirty-day patient safety did not appear to be compromised with no differences in all-cause mortality (0.6% in both groups combined), stroke/transient ischaemic attack (1.4%), life-threatening bleeding (1.3%), stage 2/3 acute kidney injury (0.7%), and valve-related readmission (1.2%). Conclusions Broad implementation of BENCHMARK practices contributes to improving efficiency of TAVI pathway reducing LoS and costs without compromising patient safety.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001194078200001; volume:45; issue:21; firstpage:1904; lastpage:1916; numberofpages:13; journal:EUROPEAN HEART JOURNAL; https://hdl.handle.net/11585/983424; https://academic.oup.com/eurheartj/article/45/21/1904/7637935
DOI: 10.1093/eurheartj/ehae147
Availability: https://hdl.handle.net/11585/983424; https://doi.org/10.1093/eurheartj/ehae147; https://academic.oup.com/eurheartj/article/45/21/1904/7637935
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.8A9F170C
Database: BASE