| Title: |
High-resolution fMRI reveals a dorsal brain pathway selective for conspecific vocalizations in macaques |
| Authors: |
Froesel, Mathilda; Ikuchi, Koh; Zhu, Qi; Wang, Haiyan; Hauser, Marc; Ben Hamed, Suliann; Vanduffel, Wim |
| Contributors: |
Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven); Kyōto daigaku = Kyoto University; Service NEUROSPIN (NEUROSPIN); Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT); Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA); Chinese Academy of Sciences Beijing (CAS); Falmouth University; Institut des sciences cognitives Marc Jeannerod - Centre de neuroscience cognitive - UMR5229 (ISC-MJ); Université Claude Bernard Lyon 1 (UCBL); Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS); Athinoula A. Martinos Center for Biomedical Imaging; Harvard Medical School Boston (HMS)-Massachusetts General Hospital Boston; This work received funding from KU Leuven C14/21/111, IDN/20/016, C3/21/027, CELSA/24/020; Fonds Wetenschappelijk Onderzoek-Vlaanderen (FWO-Flanders) 12AF124N, G0E0520N, G0C1920N; and the European Union’s Horizon 2020 Framework Programme for Research H2020, grant EBRAINS2.0.; European Project: 101147319,HORIZON-INFRA-2022-SERV-B-01,HORIZON-INFRA-2022-SERV-B-01,EBRAINS 2.0(2024) |
| Source: |
EISSN: 2837-6056 ; Imaging Neuroscience ; https://hal.science/hal-05403596 ; Imaging Neuroscience, 2025, 3, ⟨10.1162/IMAG.a.108⟩ |
| Publisher Information: |
CCSD; MIT Press |
| Publication Year: |
2025 |
| Collection: |
HAL Lyon 1 (University Claude Bernard Lyon 1) |
| Subject Terms: |
macaques; vocalizations; fMRI; dorsal premotor cortex; parieto-temporal cortex; [SCCO.NEUR]Cognitive science/Neuroscience |
| Description: |
International audience ; Understanding the neural basis of social communication and vocal perception in primates is a key challenge in systems neuroscience. Vocalizations are fundamental for communication, and several cortical areas, known as “voice patches,” have been identified as being sensitive to conspecific vocalizations in primates, vital for distinguishing species-specific calls. While the dorsal stream’s role in complex auditory-motor functions and human speech processing is established, its specific contribution to processing species-specific vocalizations in non-human primates remains unclear. Using high-resolution fMRI (0.6 mm isotropic voxels), we investigated brain regions involved in processing vocalizations in awake rhesus monkeys exposed to coos, screams, and aggressive calls, among control sounds. Our analyses revealed a widespread network involved in vocalization processing, encompassing auditory-associated areas including the core and belt auditory cortices, as well as premotor, and somatosensory-related areas. Moreover, we found selective activation in the caudal part of the lateral sulcus (area Tpt) and the dorsal premotor cortex (area 6DR/F2) in response to vocalizations. Also, the population responses in these areas could discriminate between different vocalizations. Our results enhance our understanding of the neural basis of vocal communication in primates. Specifically, they highlight the involvement of a voice-related dorsal network in macaques, including Tpt and part of 6DR/F2, in processing the acoustic features of salient vocal stimuli, potentially linking them to motor representations. These findings provide insights into potential evolutionary precursors of auditory-motor pathways that support complex auditory communication systems in primates, including human speech. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40821761; info:eu-repo/grantAgreement//101147319/EU/EBRAINS 2.0: A Research Infrastructure to Advance Neuroscience and Brain Health/EBRAINS 2.0; PUBMED: 40821761; PUBMEDCENTRAL: PMC12351310 |
| DOI: |
10.1162/IMAG.a.108 |
| Availability: |
https://hal.science/hal-05403596; https://hal.science/hal-05403596v1/document; https://hal.science/hal-05403596v1/file/2025_ImagingNeuro_Froesel.pdf; https://doi.org/10.1162/IMAG.a.108 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.8AE61DCC |
| Database: |
BASE |