Late-acquired incomplete stent apposition after everolimus-eluting stent versus sirolimus-eluting stent implantation in patients with non-ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction (APPOSITION-AMI)
| Title: | Late-acquired incomplete stent apposition after everolimus-eluting stent versus sirolimus-eluting stent implantation in patients with non-ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction (APPOSITION-AMI) |
|---|---|
| Authors: | Hur SH; Lee BR; Kim SW; Hong YJ; Bae JH; Choi D; Kang HJ; Choi SY; Lee SG; Kim DI; Park JS; Rha SW |
| Contributors: | 허승호; Hur, Seung Ho; Dept. of Internal Medicine (내과학) |
| Publisher Information: | School of Medicine |
| Publication Year: | 2016 |
| Collection: | Keimyung University Medical Library: KUMeL Repository |
| Subject Terms: | myocardial infarction; stents; ultrasonography |
| Description: | AIMS: Our aim was to evaluate the incidence and clinical outcomes of late-acquired incomplete stent apposition (LAISA) after implantation of first- and second-generation drug-eluting stents in patients with acute myocardial infarction (AMI). METHODS AND RESULTS: Late-Acquired incomplete stent aPPOsition after everolimus-eluting stent versus sirolimus-eluting Stent ImplanTatION in pAtients with non ST-segment elevation Myocardial Infarction and ST-segment elevation myocardial infarction (APPOSITION-AMI) was a prospective, randomised study comparing LAISA after everolimus-eluting stent (EES) and sirolimus-eluting stent (SES) implantation in AMI patients. Intravascular ultrasound examination was serially performed post-procedurally and at eight-month follow-up in 195 AMI patients (205 native coronary lesions: 100 EES; 105 SES). LAISA was observed in 6.0% and 16.2% of EES- vs. SES-treated lesions (p=0.021), respectively. In 64.7% of SES-treated lesions, LAISA was caused by positive remodelling, whereas thrombus dissolution or plaque reduction was observed in 66.7% of EES-treated lesions. Among patients with LAISA, MACE developed in one (4.5%) in the SES group with no ST in either group up to one year. CONCLUSIONS: The incidence of LAISA was lower in AMI patients treated with EES as compared to SES, mainly secondary to positive remodelling in SES- but not EES-treated lesions. Patients with LAISA in both groups showed a very low MACE incidence at one-year follow-up. ; prohibition |
| Document Type: | article in journal/newspaper |
| Language: | unknown |
| ISSN: | 1774-024X |
| Relation: | EuroIntervention, Vol.12(8) : e979-e986, 2016; oak-2017-0109; http://kumel.medlib.dsmc.or.kr/handle/2015.oak/32694; https://www.pcronline.com/eurointervention/105th_issue/volume-12/number-8/161/late-acquired-incomplete-stent-apposition-after-everolimus-eluting-stent-versus-sirolimus-eluting-stent-implantation-in-patients-with-non-st-segment-elevation-myocardial-infarction-and-st-segment-elevation-myocardial-infarction-apposition-ami.html |
| DOI: | 10.4244/EIJY15M09_12 |
| Availability: | http://kumel.medlib.dsmc.or.kr/handle/2015.oak/32694; https://doi.org/10.4244/EIJY15M09_12; https://www.pcronline.com/eurointervention/105th_issue/volume-12/number-8/161/late-acquired-incomplete-stent-apposition-after-everolimus-eluting-stent-versus-sirolimus-eluting-stent-implantation-in-patients-with-non-st-segment-elevation-myocardial-infarction-and-st-segment-elevation-myocardial-infarction-apposition-ami.html |
| Rights: | BY_NC_ND ; http://creativecommons.org/licenses/by-nc-nd/2.0/kr |
| Accession Number: | edsbas.8C822BD2 |
| Database: | BASE |