The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.
| Title: | The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. |
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| Authors: | L. Shi; G. Campbell; W. D. Jones; F. Campagne; Z. Wen; S. J. Walker; Z. Su; T. Chu; F. M. Goodsaid; L. Pusztai; J. D. Shaughnessy; A. Oberthuer; R. S. Thomas; R. S. Paules; M. Fielden; B. Barlogie; W. Chen; P. Du; M. Fischer; C. Furlanello; B. D. Gallas; X. Ge; D. B. Megherbi; W. F. Symmans; M. D. Wang; J. Zhang; H. Bitter; B. Brors; P. R. Bushel; M. Bylesjo; M. Chen; J. Cheng; J. Chou; T. S. Davison; M. Delorenzi; Y. Deng; V. Devanarayan; D. J. Dix; J. Dopazo; K. C. Dorff; F. Elloumi; J. Fan; S. Fan; X. Fan; H. Fang; N. Gonzaludo; K. R. Hess; H. Hong; J. Huan; R. A. Irizarry; R. Judson; D. Juraeva; S. Lababidi; C. G. Lambert; L. Li; Y. Li; Z. Li; S. M. Lin; G. Liu; E. K. Lobenhofer; J. Luo; W. Luo; M. N. McCall; Y. Nikolsky; G. A. Pennello; R. G. Perkins; R. Philip; V. Popovici; N. D. Price; F. Qian; A. Scherer; T. Shi; W. Shi; J. Sung; D. Thierry Mieg; J. Thierry Mieg; V. Thodima; J. Trygg; L. Vishnuvajjala; S. J. Wang; J. Wu; Y. Wu; Q. Xie; W. A. Yousef; L. Zhang; X. Zhang; S. Zhong; Y. Zhou; S. Zhu; D. Arasappan; W. Bao; A. B. Lucas; F. Berthold; R. J. Brennan; A. Buness; J. G. Catalano; C. Chang; R. Chen; Y. Cheng; J. Cui; W. Czika; X. Deng; D. Dosymbekov; R. Eils; Y. Feng; J. Fostel; S. Fulmer Smentek; J. C. Fuscoe; L. Gatto; W. Ge; D. R. Goldstein; L. Guo; D. N. Halbert; J. Han; S. C. Harris; C. Hatzis; D. Herman; J. Huang; R. V. Jensen; R. Jiang; C. D. Johnson; G. Jurman; Y. Kahlert; S. A. Khuder; M. Kohl; J. Li; M. Li; Q. Li; S. Li; J. Liu; Y. Liu; Z. Liu; L. Meng; M. Madera; F. Martinez Murillo; I. Medina; J. Meehan; K. Miclaus; R. A. Moffitt; D. Montaner; P. Mukherjee; G. J. Mulligan; P. Neville; T. Nikolskaya; B. Ning; G. P. Page; J. Parker; R. M. Parry; X. Peng; R. L. Peterson; J. H. Phan; B. Quanz; Y. Ren; S. Riccadonna; A. H. Roter; F. W. Samuelson; M. M. Schumacher; J. D. Shambaugh; Q. Shi; R. Shippy; S. Si; A. Smalter; C. Sotiriou; M. Soukup; F. Staedtler; G. Steiner; T. H. Stokes; Q. Sun; P. Tan; R. Tang; Z. Tezak; B. Thorn; M. Tsyganova; Y. Turpaz; S. C. Vega; Visintainer, Roberto; J. v. Frese; C. Wang; E. Wang; J. Wang; W. Wang; F. Westermann; J. C. Willey; M. Woods; S. Wu; N. Xiao; J. Xu; L. Xu; L. Yang; X. Zeng; M. Zhang; C. Zhao; R. K. Puri; U. Scherf; W. Tong; R. D. Wolfinger; M. A. Q.; Demichelis, Francesca |
| Contributors: | Shi, L.; Campbell, G.; Jones, W. D.; Campagne, F.; Wen, Z.; Walker, S. J.; Su, Z.; Chu, T.; Goodsaid, F. M.; Pusztai, L.; Shaughnessy, J. D.; Oberthuer, A.; Thomas, R. S.; Paules, R. S.; Fielden, M.; Barlogie, B.; Chen, W.; Du, P.; Fischer, M.; Furlanello, C.; Gallas, B. D.; Ge, X.; Megherbi, D. B.; Symmans, W. F.; Wang, M. D.; Zhang, J.; Bitter, H.; Brors, B.; Bushel, P. R.; Bylesjo, M.; Chen, M.; Cheng, J.; Chou, J.; Davison, T. S.; Delorenzi, M.; Deng, Y.; Devanarayan, V.; Dix, D. J.; Dopazo, J.; Dorff, K. C.; Elloumi, F.; Fan, J.; Fan, S.; Fan, X.; Fang, H.; Gonzaludo, N.; Hess, K. R.; Hong, H.; Huan, J.; Irizarry, R. A.; Judson, R.; Juraeva, D.; Lababidi, S.; Lambert, C. G.; Li, L.; Li, Y.; Li, Z.; Lin, S. M.; Liu, G.; Lobenhofer, E. K.; Luo, J.; Luo, W.; Mccall, M. N.; Nikolsky, Y.; Pennello, G. A.; Perkins, R. G.; Philip, R.; Popovici, V.; Price, N. D.; Qian, F.; Scherer, A.; Shi, T.; Shi, W.; Sung, J.; Thierry Mieg, D.; Thierry Mieg, J.; Thodima, V.; Trygg, J.; Vishnuvajjala, L.; Wang, S. J.; Wu, J.; Wu, Y.; Xie, Q.; Yousef, W. A.; Zhang, L.; Zhang, X.; Zhong, S.; Zhou, Y.; Zhu, S.; Arasappan, D.; Bao, W.; Lucas, A. B.; Berthold, F.; Brennan, R. J.; Buness, A.; Catalano, J. G.; Chang, C.; Chen, R.; Cheng, Y. |
| Publisher Information: | USA |
| Publication Year: | 2010 |
| Collection: | Università degli Studi di Trento: CINECA IRIS |
| Subject Terms: | Animals; Breast Neoplasm; diagnosis/genetics; Disease Model; Animal; Female; Gene Expression Profiling; methods/standards; Guidelines as Topic; Humans; Liver Disease; etiology/genetics/pathology; Lung Disease; Multiple Myeloma; Neoplasm; diagnosis/genetics/mortality; Neuroblastoma; Oligonucleotide Array Sequence Analysi; Predictive Value of Tests; Quality Control; Rats; Survival Analysis |
| Description: | Gene expression data from microarrays are being applied to predict preclinical and clinical endpoints, but the reliability of these predictions has not been established. In the MAQC-II project, 36 independent teams analyzed six microarray data sets to generate predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans. In total, >30,000 models were built using many combinations of analytical methods. The teams generated predictive models without knowing the biological meaning of some of the endpoints and, to mimic clinical reality, tested the models on data that had not been used for training. We found that model performance depended largely on the endpoint and team proficiency and that different approaches generated models of similar performance. The conclusions and recommendations from MAQC-II should be useful for regulatory agencies, study committees and independent investigators that evaluate methods for global gene expression analysis. |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/20676074; info:eu-repo/semantics/altIdentifier/wos/WOS:000280757500023; volume:28; firstpage:827; lastpage:838; numberofpages:11; journal:NATURE BIOTECHNOLOGY; https://hdl.handle.net/11572/88960 |
| Availability: | https://hdl.handle.net/11572/88960 |
| Accession Number: | edsbas.8D1ACCEA |
| Database: | BASE |