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A Bayesian approach to competing risks analysis with masked cause of death

Title: A Bayesian approach to competing risks analysis with masked cause of death
Authors: Sen, Ananda; Banerjee, Mousumi; Li, Yun; Noone, Anne-Michelle
Contributors: Department of Statistics and Center for Statistical Consultation and Research, University of Michigan, Ann Arbor, MI, U.S.A.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, U.S.A.; Department of Biostatistics, Bioinformatics, and Biomathematics and Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, U.S.A.
Publisher Information: John Wiley & Sons, Ltd.
Publication Year: 2010
Collection: University of Michigan: Deep Blue
Subject Terms: Mathematics and Statistics; Medicine (General); Statistics and Numeric Data; Public Health; Health Sciences; Science; Social Sciences
Description: Cause-specific analyses under a competing risks framework have received considerable attention in the statistical literature. Such analyses are useful for comparing mortality patterns across racial and/or age groups. Earlier work in the statistical literature focused on the situation when the cause of death is known. A challenging twist to the problem arises when the cause of death is not known exactly, but can be narrowed down to a set of potential causes that do not necessarily act independently. This phenomenon, referred to as masking , is often the result of incomplete or partial information on death certificates and/or lack of routine autopsy on every patient. In this article we propose a semiparametric Bayesian approach for analyzing competing risks survival data with masked cause of death. The models proposed do not assume independence among the causes, and are valid for an arbitrary number of causes. Further, the Bayesian approach is flexible in allowing a general pattern of missingness for the cause of death. We illustrate our methodology using breast cancer data from the Detroit Surveillance, Epidemiology, and End Results registry. Copyright © 2010 John Wiley & Sons, Ltd. ; Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/77443/1/3894_ftp.pdf
Document Type: article in journal/newspaper
File Description: 203061 bytes; 3118 bytes; application/pdf; text/plain
Language: unknown
Relation: http://hdl.handle.net/2027.42/77443; Statistics in Medicine
DOI: 10.1002/sim.3894
Availability: http://hdl.handle.net/2027.42/77443; https://doi.org/10.1002/sim.3894
Rights: IndexNoFollow
Accession Number: edsbas.8D4211B
Database: BASE