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PREVALENCE OF 'BORDERLINE' VALUES OF CARDIOVASCULAR RISK FACTORS IN THE CLINICAL PRACTICE OF GENERAL MEDICINE IN ITALY: RESULTS OF THE BORDERLINE STUDY.

Title: PREVALENCE OF 'BORDERLINE' VALUES OF CARDIOVASCULAR RISK FACTORS IN THE CLINICAL PRACTICE OF GENERAL MEDICINE IN ITALY: RESULTS OF THE BORDERLINE STUDY.
Authors: Tocci, G; Ferruccia, A; Passerini, J; Bellotti, P; Bruno, G; Cosentino, F; Crepaldi, G; Giannottasio, C; Modena, MG; Nati, G; Tiengo, A; Trimarco, B; Vannuzzo, D; V. olpe, M.; AVERNA, Maurizio
Contributors: Tocci, G; Ferruccia, A; Passerini, J; Averna, M; Bellotti, P; Bruno, G; Cosentino, F; Crepaldi, G; Giannottasio, C; Modena, MG; Nati, G; Tiengo, A; Trimarco, B; Vannuzzo, D; V olpe, M
Publisher Information: Springer International; NZ
Publication Year: 2011
Collection: IRIS Università degli Studi di Palermo
Subject Terms: borderline risk; high-normal risk; cardiovascular prevention; global cardiovascular risk; blood pressure; cholesterol; glucose; Settore MED/09 - Medicina Interna
Description: INTRODUCTION: The prevalence of patients with 'borderline' levels of cardiovascular risk factors has been rarely investigated, being often reported in studies evaluating abnormal values of these parameters. The BORDERLINE study represents a pilot experience to primarily identify the prevalence of 'high-normal' conditions, such as pre-hypertension, lipid and glucose levels in the upper range of normality in the setting of general practice in Italy. AIM: The aim of this study was to evaluate the prevalence of patients with 'borderline' values of cardiovascular risk factors in Italy. METHODS: Involved physicians were asked to evaluate the first 20 outpatients, consecutively seen in June 2009. Data were collected in a study-designed case-report form, in which physicians identified thresholds rather than reported absolute values of several clinical parameters. High-normal values were defined as follows: blood pressure (BP) 130-140/85-90 mmHg; total cholesterol 180-200 mg/dL; low-density lipoprotein cholesterol (LDL-C) 130-150 mg/dL; high-density lipoprotein cholesterol (HDL-C) 30-40 mg/dL in males and 40-50 mg/dL in females; triglycerides 130-150 mg/dL and fasting glucose 100-110 mg/dL. RESULTS: Fifty-three Italian physicians provided valuable clinical data on 826 individual outpatients, among which 692 (83.7%, 377 women, mean age 60.9 ± 13.2 years, body mass index 26.6 ± 5.0 kg/m2) were included in the present analysis. Prevalence of borderline values of systolic BP and total cholesterol levels were at least comparable with those in the normal limits of the corresponding parameters, whereas prevalence of borderline diastolic BP, LDL-C, HDL-C, triglycerides and fasting glucose levels was significantly lower than that of normal values, but higher than that of abnormal values of the corresponding parameters. CONCLUSIONS: Using this sample of healthy subjects in the setting of general practice in Italy, our results demonstrated a relatively high prevalence of borderline values of cardiovascular risk factors, which was ...
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000442290100002; volume:18; issue:2; firstpage:43; lastpage:51; numberofpages:8; journal:HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION; https://hdl.handle.net/10447/94442
DOI: 10.2165/11593420-000000000-00000
Availability: https://hdl.handle.net/10447/94442; https://doi.org/10.2165/11593420-000000000-00000
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.8EB48CEA
Database: BASE