Viral circRNA identification in three models of BLV infections.
| Title: | Viral circRNA identification in three models of BLV infections. |
|---|---|
| Authors: | Alexis S. Chasseur; Maxime Bellefroid; Mathilde Galais; Meijiao Gong; Pierre Lombard; Sarah Mathieu; Amandine Pecquet; Estelle Plant; Camille Ponsard; Laure Vreux; Carlo Yague-Sanz; Benjamin G. Dewals; Nicolas A. Gillet; Benoît Muylkens; Carine M. Van Lint; Damien Coupeau |
| Publication Year: | 2025 |
| Subject Terms: | Medicine; Microbiology; Genetics; Molecular Biology; Evolutionary Biology; Immunology; Infectious Diseases; Virology; Biological Sciences not elsewhere classified; +non%22">xlink "> non; unconventional splicing mechanisms; sanger sequencings validated; recent attention focused; obtained novel insights; initially anticipated due; identify backsplicing events; human pathogens belonging; existing datasets encompassing; conserved eukaryotic patterns; coding rnas play; viral infection cycles; viral genomes include; unique viral characteristics; rna sequencing data; developed bioinformatic tool; various viral families; bioinformatic pipeline tailored; families |
| Description: | (A) CircRNAs mapped to the BLV genome after a transfection of the viral genome in the HEK 293T cell line. (B) CircRNAs mapped to the BLV genome during a productive infection in the L267 LTaxSN cell line. (C) CircRNAs mapped to the BLV genome during a productive infection in the YR2 LTaxSN cell line. Relevant ORFs were indicated under the graphs on the same scale as the viral genome. For graphical purposes, the splicings of the tax and rex genes were not depicted. The Y axis indicates the abundance of unique circRNAs in reads mapping the backsplice junctions per billion of reads mapping on the viral BLV genome. (TIF) |
| Document Type: | still image |
| Language: | unknown |
| Relation: | https://figshare.com/articles/figure/Viral_circRNA_identification_in_three_models_of_BLV_infections_/30105308 |
| DOI: | 10.1371/journal.ppat.1013448.s002 |
| Availability: | https://doi.org/10.1371/journal.ppat.1013448.s002; https://figshare.com/articles/figure/Viral_circRNA_identification_in_three_models_of_BLV_infections_/30105308 |
| Rights: | CC BY 4.0 |
| Accession Number: | edsbas.8EF262A8 |
| Database: | BASE |