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Success Predictors of Endoscopic Sleeve Gastroplasty

Title: Success Predictors of Endoscopic Sleeve Gastroplasty
Authors: Matteo M. V.; Bove V.; Ciasca G.; Carlino G.; Vinti L.; Pontecorvi V.; Papi M.; Spada C.; Boskoski I.
Contributors: Matteo, Maria Valeria; Bove, Vincenzo; Ciasca, Gabriele; Carlino, Giorgio; Di Santo, R.; Vinti, Laila; Polidori, G.; Pontecorvi, Valerio; Papi, Massimiliano; Spada, Cristiano; Boskoski, Ivo
Publisher Information: SPRINGER
Publication Year: 2024
Collection: Università Cattolica del Sacro Cuore: PubliCatt
Subject Terms: ESG; Endoscopic sleeve gastroplasty; Obesity; Predictors; Settore MED/12 - GASTROENTEROLOGIA; Settore MEDS-10/A - Gastroenterologia
Description: Objective Endoscopic sleeve gastroplasty (ESG) is a minimally invasive procedure that proved to be safe and effective in obesity treatment. However, not all subjects respond to treatment in the same way, and, with a view to personalized care, it is essential to identify predictors of success or failure. Methods A retrospective 2-year followed-up cohort of ESG subjects was analyzed to investigate the presence of any baseline or early indicators of long-term optimal or suboptimal ESG outcomes. Results A total of 315 subjects (73% women) were included, with 73% of patients exhibiting an Excess weight loss percentage (%EWL) >25% at the 24 months. Neither demographic parameters (age and sex), smoking habits, and menopause in women nor the presence of comorbidities proved potential predictive value. Interestingly, the %EWL at 1 month after ESG was the strongest predictor of 24-month therapeutic success. Subsequently, we estimated an "early threshold for success" for 1 month-%EWL by employing Youden's index method. Conclusions ESG is a safe and effective bariatric treatment that can be offered to a wide range of subjects. Early weight loss seems to impact long-term ESG results significantly and may allow proper early post-operative care optimization.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/38451369; info:eu-repo/semantics/altIdentifier/wos/WOS:001177464200001; volume:34; issue:5; firstpage:1496; lastpage:1504; numberofpages:9; issueyear:2024; journal:OBESITY SURGERY; https://hdl.handle.net/10807/297365
DOI: 10.1007/s11695-024-07109-4
Availability: https://hdl.handle.net/10807/297365; https://doi.org/10.1007/s11695-024-07109-4
Rights: info:eu-repo/semantics/openAccess ; license:Creative commons ; license uri:http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.8F2BDCF2
Database: BASE