Development of a genetically tailored implantation hepatocellular carcinoma model in Oncopigs by somatic cell CRISPR editing
| Title: | Development of a genetically tailored implantation hepatocellular carcinoma model in Oncopigs by somatic cell CRISPR editing |
|---|---|
| Authors: | Lobna Elkhadragy; Maximillian J. Carlino; Luke R. Jordan; Thomas Pennix; Nahed Ismail; Grace Guzman; Jonathan P. Samuelson; Lawrence B. Schook; Kyle M. Schachtschneider; Ron C. Gaba |
| Source: | Disease Models & Mechanisms, Vol 18, Iss 1 (2025) |
| Publisher Information: | The Company of Biologists |
| Publication Year: | 2025 |
| Collection: | Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: | hcc model; porcine model; large-animal model; crispr gene editing; precision models; Medicine; Pathology; RB1-214 |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | http://dmm.biologists.org/content/18/1/dmm052079; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411; https://doaj.org/article/5ab3aff3f2a84ffab00acc9817667f44 |
| DOI: | 10.1242/dmm.052079 |
| Availability: | https://doi.org/10.1242/dmm.052079; https://doaj.org/article/5ab3aff3f2a84ffab00acc9817667f44 |
| Accession Number: | edsbas.90219CD4 |
| Database: | BASE |