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Recanalization of the Duodenum Following a High-Grade Post-Laparoscopic Cholecystectomy Duodenal Injury: Personalized Approach Presentation and Systematic Review of Management Options

Title: Recanalization of the Duodenum Following a High-Grade Post-Laparoscopic Cholecystectomy Duodenal Injury: Personalized Approach Presentation and Systematic Review of Management Options
Authors: Nefeli K. Tomara; Christos Doudakmanis; Dionysios Prevezanos; Ioannis Lymperis; Stylianos Kykalos; Gerasimos Tsourouflis; Chrysovalantis Vergadis; Nikolaos I. Nikiteas; Dimitrios Dimitroulis
Source: Journal of Personalized Medicine ; Volume 16 ; Issue 3 ; Pages: 131
Publisher Information: Multidisciplinary Digital Publishing Institute
Publication Year: 2026
Collection: MDPI Open Access Publishing
Subject Terms: duodenal injury; duodenal perforation; post-laparoscopic cholecystectomy
Description: Background: Laparoscopic cholecystectomy is considered the gold standard surgical technique for the treatment of gallbladder diseases worldwide. Nonetheless, despite its safety and popularity, it comes with certain complications. Duodenal injury is an extremely rare, but potentially fatal complication. The rarity of duodenal injuries, combined with under-reporting of incidents, has resulted in a scarcity of references in the international literature. Case Presentation: We present the case of a 72-year-old male patient, initially subjected to laparoscopic cholecystectomy that was intraoperatively converted to open cholecystectomy. During the laparoscopic approach, the patient experienced a major duodenal injury, which was treated intraoperatively using primary suturing. Upon postoperative failure of the indicated surgical treatment, extended individualized salvage surgery was performed, with an ultimately favorable outcome. Methods: When assessing the overall implications of this case, we conducted a review of the published literature in English, published up to November 2025 on patients with duodenal injury after exclusively laparoscopic cholecystectomy. Results: We then categorized the 105 cases described based on the therapeutic approach: surgical, conservative, and endoscopic, with a view to attempt to classify the available therapeutic options based on the time of diagnosis, the patient’s performance status, and the size and location of the injury. Conclusions: While laparoscopic cholecystectomy is a common surgical procedure, duodenal injuries remain rare. The treatment approach highly depends on the time of injury recognition, site and extent of the injury and patient’s status. Treatment should be personalized based on the aforementioned parameters.
Document Type: text
File Description: application/pdf
Language: English
Relation: Personalized Therapy in Clinical Medicine; https://dx.doi.org/10.3390/jpm16030131
DOI: 10.3390/jpm16030131
Availability: https://doi.org/10.3390/jpm16030131
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.906BFD1F
Database: BASE