| Title: |
Surgical versus sequential hybrid treatment of carotid body tumors |
| Authors: |
Amato B.; Compagna R.; Florio A.; Calemma F.; Rocca A.; Salzano F.; Brongo S.; Gasbarro V.; Aprea G. |
| Contributors: |
Amato, B.; Compagna, R.; Florio, A.; Calemma, F.; Rocca, A.; Salzano, F.; Brongo, S.; Gasbarro, V.; Aprea, G. |
| Publication Year: |
2020 |
| Collection: |
Università degli Studi della Campania "Luigi Vanvitelli": CINECA IRIS V: |
| Subject Terms: |
AKT/mTOR; Apoptosi; PBF; Proliferation; Wnt3a/β-catenin |
| Description: |
Carotid body tumor (CBT) are slow-growing tumors that develop in the cervical region at the carotid bifurcation. In a randomized study, 33 patients were treated for CBT excision: 10 patients performed preoperative embolization (PE) and 23 were treated only by isolated traditional surgery (N-PE). The first group includes patients undergoing preoperative embolization. The second group of patients (N-PE) included 11 males and 12 females. Intraoperative complications were lower in patients treated with a hybrid procedure (PE): sections of the cranial nerves were recorded in 7% of cases compared to 12% of the surgical procedure (P-value = 0.72); while the reversible nerve lesions (P value = 0.21) and the permanent ones (P value = 0.46), were instead similar in both procedures. The comparative blood loss during the operative procedure shows a P-value of 0.02. Operating times, reversible damage of the cranial nerves, incidence of stroke (0% vs1%, P value> 0.99) and post-operative hospital stay (4.1 vs. 4.2 days, P value = 0.91) did not show differences in the two groups of patients. The analysis of the results detects pre-operative embolization of CBT in reducing intraoperative blood loss and resection of the cranial nerves. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/31934642; info:eu-repo/semantics/altIdentifier/wos/WOS:000505250300001; volume:14; issue:1; firstpage:968; lastpage:976; numberofpages:9; journal:OPEN MEDICINE; https://hdl.handle.net/11591/439016 |
| DOI: |
10.1515/med-2019-0115 |
| Availability: |
https://hdl.handle.net/11591/439016; https://doi.org/10.1515/med-2019-0115 |
| Accession Number: |
edsbas.907906CC |
| Database: |
BASE |