| Title: |
The impact of cancer survivors’ extra risk of noncancer mortality on net survival estimation |
| Authors: |
Botta, Laura; Capocaccia, Riccardo; Bernasconi, Alice; Rossi, Silvia; Galceran, Jaume; Dal Maso, Luigino; Lepage, Come; Molinié, Florence; Bouvier, Anne-Marie; Marcos-Gragera, Rafael; Vener, Claudia; Guevara, Marcela; Murray, Deirdre; Ragusa, Rosalia; Gatta, Gemma; Jooste, Valerie; Hackl, M; Van Eycken, E; Van Damme, N; Valerianova, Z; Sekerija, M; Scoutellas, V; Demetriou, A; Dušek, L; Krejici, D; Storm, H; Mägi, M; Innos, K; Pitkäniemi, J; Velten, M; Troussard, X; Bouvier, A M; Jooste, V; Guizard, A V; Launoy, G; Dabakuyo Yonli, S; Maynadié, M; Woronoff, A S; Nousbaum, J B; Coureau, G; Monnereau, A; Baldi, I; Hammas, K; Tretarre, B; Colonna, M; Plouvier, S; D'Almeida, T; Molinié, F; Cowppli-Bony, A; Bara, S |
| Contributors: |
Italian Association for Cancer Research; French Institut National du Cancer; Italian Association of Cancer Research; Innovative Partnership for Action Against Cancer |
| Source: |
American Journal of Epidemiology ; volume 194, issue 11, page 3316-3324 ; ISSN 0002-9262 1476-6256 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Relative survival (RS) with the general population as the reference is commonly used to estimate net survival (NS). However, cancer patients may face an increased risk of noncancer death compared to cancer-free individuals. We evaluate the impact of considering this relative risk (RR) on NS estimation. First, we compared selected NS values to generated RS under various theoretical scenarios, considering different RR, NS, age at diagnosis, time since diagnosis, and sex. Then, differences between NS and RS for 3 cancers were analyzed from cure model-based estimates using EUROCARE-6 data. We observed differences between RS and the true value of NS, larger for longer time since diagnosis, older patients, and higher NS. For head and neck cancer, the smallest differences were for young female patients at 5 years from diagnosis (4%) and the highest (32%) for older patients. For colorectal cancer, differences were |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/aje/kwaf148 |
| DOI: |
10.1093/aje/kwaf148/64081146/kwaf148.pdf |
| Availability: |
https://doi.org/10.1093/aje/kwaf148; https://academic.oup.com/aje/advance-article-pdf/doi/10.1093/aje/kwaf148/64081146/kwaf148.pdf; https://academic.oup.com/aje/article-pdf/194/11/3316/64081146/kwaf148.pdf |
| Rights: |
https://creativecommons.org/licenses/by-nc/4.0/ |
| Accession Number: |
edsbas.9085056 |
| Database: |
BASE |