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Constructing the dependence between the Young’s modulus value and the Hounsfield units of spongy tissue of human femoral heads

Title: Constructing the dependence between the Young’s modulus value and the Hounsfield units of spongy tissue of human femoral heads
Authors: Bessonov, Leonid Valentinovich; Дмитриев , Павел Олегович; Dol, Aleksandr Viktorovich; Ivanov, Dmitriy V.; Kirillova, Irina Vasil'evna; Kossovich, Leonid Yurevich; Титова, Юлия Ивановна; Ульянов, Владимир Юрьевич; Kharlamov, Aleksandr Vladimirovich
Source: Известия Саратовского университета. Новая серия: Математика. Механика. Информатика, Vol 21, Iss 2, Pp 182-193 (2021)
Publisher Information: Saratov State University
Publication Year: 2021
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: quantitative computed tomography; bone mineral density; hounsfield units; young’s modulus; Mathematics; QA1-939
Description: Patient-specific biomechanical modeling requires not only the geometric model of the studied object of a particular patient, but also the mechanical properties of its tissues. Quantitative computed tomography provides the initial data for geometric modeling, as well as data on X-ray density (Hounsfield units) of the object. It is known that Hounsfield units correlate with mineral density of the scanned objects, as well as with their strength properties. The aim of this study was to determine the relationship between Hounsfield units and Young's modulus values of human femoral heads spongy tissue.This study was conducted on samples of femur bones spongy tissue. The tissue was obtained from patients who underwent total hip replacement for coxarthrosis. Samples were scanned on a Toshiba Aquilion 64 computed tomograph and then subjected to uniaxial compression on an Instron 5944 universal testing machine.As a result of the study, the average Hounsfield units were obtained for each sample, as well as the Young's modules values. Regression dependencies were calculated linking the Hounsfield units and the Young's modulus values of samples of femoral heads spongy tissue in different types of diseases.The obtained dependences allow one to determine Young's modulus value of femoral heads spongy bone noninvasively for a particular patient, depending on his disease, and using it in the process of preoperative planning. Also, the obtained dependencies can be used in biomechanical modeling of diseases and injuries of vertebral-pelvic complex of a particular patient treatment and can be implemented in medical decision support system in surgery of vertebral-pelvic complex.
Document Type: article in journal/newspaper
Language: English; Russian
Relation: https://mmi.sgu.ru/sites/mmi.sgu.ru/files/text-pdf/2021/05/182-193bessonov_et_al.pdf; https://doaj.org/toc/1816-9791; https://doaj.org/toc/2541-9005; https://doaj.org/article/0eaf0a30c67d4d529051ebe298f6ee3d
DOI: 10.18500/1816-9791-2021-21-2-182-193
Availability: https://doi.org/10.18500/1816-9791-2021-21-2-182-193; https://doaj.org/article/0eaf0a30c67d4d529051ebe298f6ee3d
Accession Number: edsbas.930E00EB
Database: BASE