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Current trends in the application of causal inference methods to pooled longitudinal non-randomised data: a protocol for a methodological systematic review

Title: Current trends in the application of causal inference methods to pooled longitudinal non-randomised data: a protocol for a methodological systematic review
Authors: Yeboah, Edmund; Mauer, Nicole Sibilla; Hufstedler, Heather; Carr, Sinclair; Matthay, Ellicott C; Maxwell, Lauren; Rahman, Sabahat; Debray, Thomas; de Jong, Valentijn M T; Campbell, Harlan; Gustafson, Paul; Jänisch, Thomas; Bärnighausen, Till
Contributors: T.H. Chan School of Medicine; Sabahat Rahman
Source: BMJ open ; 11 ; e052969 ; England
Publication Year: 2023
Collection: University of Massachusetts, Medical School: eScholarship@UMMS
Subject Terms: public health; social medicine; statistics & research methods
Description: Introduction: Causal methods have been adopted and adapted across health disciplines, particularly for the analysis of single studies. However, the sample sizes necessary to best inform decision-making are often not attainable with single studies, making pooled individual-level data analysis invaluable for public health efforts. Researchers commonly implement causal methods prevailing in their home disciplines, and how these are selected, evaluated, implemented and reported may vary widely. To our knowledge, no article has yet evaluated trends in the implementation and reporting of causal methods in studies leveraging individual-level data pooled from several studies. We undertake this review to uncover patterns in the implementation and reporting of causal methods used across disciplines in research focused on health outcomes. We will investigate variations in methods to infer causality used across disciplines, time and geography and identify gaps in reporting of methods to inform the development of reporting standards and the conversation required to effect change. Methods and analysis: We will search four databases (EBSCO, Embase, PubMed, Web of Science) using a search strategy developed with librarians from three universities (Heidelberg University, Harvard University, and University of California, San Francisco). The search strategy includes terms such as 'pool*', 'harmoniz*', 'cohort*', 'observational', variations on 'individual-level data'. Four reviewers will independently screen articles using Covidence and extract data from included articles. The extracted data will be analysed descriptively in tables and graphically to reveal the pattern in methods implementation and reporting. This protocol has been registered with PROSPERO (CRD42020143148). Ethics and dissemination: No ethical approval was required as only publicly available data were used. The results will be submitted as a manuscript to a peer-reviewed journal, disseminated in conferences if relevant, and published as part of doctoral ...
Document Type: article in journal/newspaper
File Description: application/pdf
Language: English
Relation: BMJ Open; https://doi.org/10.1136/bmjopen-2021-052969; http://hdl.handle.net/20.500.14038/51705
DOI: 10.1136/bmjopen-2021-052969
Availability: https://doi.org/10.1136/bmjopen-2021-052969; https://hdl.handle.net/20.500.14038/51705
Rights: Open access: This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:http:// creativecommons.org/ licenses/by-nc/4. 0/. ; Attribution-NonCommercial 4.0 International ; http://creativecommons.org/licenses/by-nc/4.0/
Accession Number: edsbas.93BCCC60
Database: BASE