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Diagnosis of subarachnoid haemorrhage: Systematic evaluation of CT head diagnostic accuracy and comparison with the 2022 NICE guidelines.

Title: Diagnosis of subarachnoid haemorrhage: Systematic evaluation of CT head diagnostic accuracy and comparison with the 2022 NICE guidelines.
Authors: Gillespie, Conor S; Hanrahan, John Gerrard; Mahdiyar, Roxana; Lee, Keng Siang; Ashraf, Mohammad; Alam, Ali M; Ekert, Justyna O; Mantle, Orla; Williams, Simon C; Funnell, Jonathan P; Gurusinghe, Nihal; Vindlacheruvu, Raghu; Whitfield, Peter C; Trivedi, Rikin A; Helmy, Adel; Hutchinson, Peter J
Publisher Information: Elsevier; Department of Clinical Neurosciences; //doi.org/10.1016/j.bas.2025.104200
Publication Year: 2025
Collection: Apollo - University of Cambridge Repository
Subject Terms: 6 h; CT; Computed tomography; LP; Lumbar puncture; Subarachnoid haemorrhage
Description: INTRODUCTION: Aneurysmal subarachnoid haemorrhage has a high incidence, and morbidity. It has been suggested that a negative non-contrast CT head can rule out SAH if performed within 6 h of symptom onset. RESEARCH QUESTION: What is the sensitivity of CT head at ruling out SAH stratified by time-point, and what is the potential impact of omitting Lumbar Puncture (LP) from the diagnostic pathway? MATERIAL AND METHODS: Systematic review and meta-analysis (PROSPEROID CRD42022379929). Three databases were searched, and articles published between January 2000-May 2022 included (Search date 27th November 2022). Primary objective was diagnostic accuracy of CT scans for detecting SAH at
Document Type: article in journal/newspaper
File Description: Electronic-eCollection; application/pdf
Language: English
Relation: https://www.repository.cam.ac.uk/handle/1810/383548
Availability: https://www.repository.cam.ac.uk/handle/1810/383548
Rights: Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.9580D29B
Database: BASE