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The Effects of Antimicrobial Mouthwashes on Systemic Disease: What Is the Evidence?

Title: The Effects of Antimicrobial Mouthwashes on Systemic Disease: What Is the Evidence?
Authors: Alrashdan, Mohammad S; Leao, Jair Carneiro; Doble, Amazon; McCullough, Michael; Porter, Stephen
Source: International Dental Journal (2023) (In press).
Publisher Information: Elsevier BV
Publication Year: 2023
Collection: University College London: UCL Discovery
Subject Terms: Cardiovascular disease; Chlorhexidine; Mouthwash; Periodontitis
Description: The potential association between antimicrobial mouthwash use and systemic health has gained attention in recent years with reports highlighting how some common systemic conditions are influenced by the use of different types of mouthwashes. In this context, links between mouthwash use and cardiovascular disease, diabetes mellitus, oral cancer, Alzheimer's disease, and preeclampsia have been proposed, albeit with limited levels of evidence. Chlorhexidine mouthwash in particular has been the most widely studied agent while available data on other types of over-the-counter mouthwashes are generally scarce. Furthermore, there is currently no evidence-based recommendations on the appropriate use of mouthwashes during pregnancy. This article will present the current evidence on the association between mouthwash use and the aforementioned conditions with emphasis on the mechanisms that may underlie such an association.
Document Type: article in journal/newspaper
File Description: text
Language: English
Relation: https://discovery.ucl.ac.uk/id/eprint/10180579/
Availability: https://discovery.ucl.ac.uk/id/eprint/10180579/7/Porter_1-s2.0-S0020653923004598-main.pdf; https://discovery.ucl.ac.uk/id/eprint/10180579/
Rights: open
Accession Number: edsbas.95A7C347
Database: BASE