| Title: |
Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults:A systematic review and meta-analysis |
| Authors: |
Rønnstad, Amalie Thorsti Møller; Halling-Overgaard, Anne-Sofie; Hamann, Carsten R; Skov, Lone; Egeberg, Alexander; Thyssen, Jacob P. |
| Source: |
Rønnstad , A T M , Halling-Overgaard , A-S , Hamann , C R , Skov , L , Egeberg , A & Thyssen , J P 2018 , ' Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults : A systematic review and meta-analysis ' , Journal of the American Academy of Dermatology , vol. 79 , no. 3 , pp. 448-456.e30 . https://doi.org/10.1016/j.jaad.2018.03.017 |
| Publication Year: |
2018 |
| Subject Terms: |
Adult; Anxiety/epidemiology; Child; Comorbidity; Depression/epidemiology; Dermatitis; Atopic/epidemiology; Humans; Odds Ratio; Suicidal Ideation; Suicide; Attempted; psy; demo |
| Description: |
BACKGROUND: Atopic dermatitis (AD) has been associated with anxiety and depression, but the magnitude of the alleged association is unknown. OBJECTIVE: To perform a systematic review and meta-analysis of the association between AD in children and adults and, respectively, depression, anxiety, and suicidal behavior. METHODS: The medical databases PubMed, Embase, and PsychINFO were searched. RESULTS: There was a significant association between adult AD and, respectively, depression (pooled odds ratio [OR], 2.19; 95% confidence interval [CI], 1.87-2.57) and anxiety (pooled OR, 2.19; 95% CI, 1.75-2.73). AD was also associated with depression in children (pooled OR, 1.27; 95% CI, 1.12-1.45); few data were available for anxiety. A positive association was found between AD in adults and adolescents and suicidal ideation (pooled OR, 4.32; 95% CI, 1.93-9.66). Only a few studies examined the risk of completed suicide, but the majority showed a positive association between completed suicide and AD. LIMITATIONS: Included studies used different definitions of depression and anxiety, and few studies examined the severity of AD. CONCLUSION: Depression, anxiety, and suicidal ideation should be considered by doctors when treating patients with AD. Because AD disease improvement appears to reduce these risks, this should be a priority. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://curis.ku.dk/portal/da/publications/association-of-atopic-dermatitis-with-depression-anxiety-and-suicidal-ideation-in-children-and-adults(a927e97e-b67e-42bb-bcb0-b4ab7144137b).html |
| Availability: |
https://curis.ku.dk/portal/da/publications/association-of-atopic-dermatitis-with-depression-anxiety-and-suicidal-ideation-in-children-and-adults(a927e97e-b67e-42bb-bcb0-b4ab7144137b).html |
| Rights: |
undefined |
| Accession Number: |
edsbas.95E1045F |
| Database: |
BASE |